2018
DOI: 10.1080/08927014.2018.1544246
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Pentadecanal inspired molecules as new anti-biofilm agents against Staphylococcus epidermidis

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Cited by 20 publications
(16 citation statements)
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“…Our previously reported studies showed antimicrobial and anti-biofilm activities expressed by different marine cold-adapted bacteria isolated from polar regions, especially Antarctica, against staphylococci and P. aeruginosa [ 20 , 28 , 35 , 36 , 37 ]. Herein, we demonstrated that the cell-free supernatant of an Antarctic bacterium belonging to the Psychrobacter genus, named TAE2020, strongly affected some specific virulence features of P. aeruginosa isolates from CF patients, without affecting bacterial vitality or inhibiting bacterial growth.…”
Section: Discussionmentioning
confidence: 99%
“…Our previously reported studies showed antimicrobial and anti-biofilm activities expressed by different marine cold-adapted bacteria isolated from polar regions, especially Antarctica, against staphylococci and P. aeruginosa [ 20 , 28 , 35 , 36 , 37 ]. Herein, we demonstrated that the cell-free supernatant of an Antarctic bacterium belonging to the Psychrobacter genus, named TAE2020, strongly affected some specific virulence features of P. aeruginosa isolates from CF patients, without affecting bacterial vitality or inhibiting bacterial growth.…”
Section: Discussionmentioning
confidence: 99%
“…Also, the non-bactericidal nature of a drug is purported to reduce the probability of drug resistance and mutant development (Patsilinakos et al, 2019). In light of the aforesaid fact, several non-bactericidal antibiofilm molecules from natural sources have been reported recently against S. epidermidis (Artini et al, 2017; Ricciardelli et al, 2018; Patsilinakos et al, 2019).…”
Section: Introductionmentioning
confidence: 99%
“…Various studies report strategies to prevent biofilm formation on medical devices such as catheters, sutures, stents and bone cement [ 9 , 10 , 11 , 12 ]. Several researchers are involved in the design and evaluation of specific molecules with potential therapeutic use in chronic and biofilm-related infections [ 13 , 14 ]. In particular, antimicrobial peptides (AMPs), a small bioactive protein consisting of 12–50 amino acids, seem to have emerged as promising active agents against bacteria, viruses, fungi, and also as potential chemotherapeutic agents [ 15 , 16 , 17 , 18 ].…”
Section: Introductionmentioning
confidence: 99%