Penser autrement l’observance médicamenteuse : d’une posture injonctive à une alliance thérapeutique entre le patient et le soignant – Concepts et déterminants

Baudrant-Boga, M.; Lehmann, Audrey; Allenet, Benoît

doi:10.1016/j.pharma.2011.10.003

Cited by 35 publications

(11 citation statements)

References 65 publications

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“…• Age (Vlasnik et al, 2005; Ingersoll and Cohen, 2008; Schäfer-Keller et al, 2010; Baudrant-Boga et al, 2012)…”

Section: Resultsmentioning

confidence: 99%

“…• Financial situation (Vlasnik et al, 2005; Baudrant-Boga et al, 2012) (socioeconomic status, lack of insurance, income, material resources)…”

Section: Resultsmentioning

confidence: 99%

“…• Housing situation/living situation (Vlasnik et al, 2005; Baudrant-Boga et al, 2012; Zeber et al, 2013) (lack of fixed address, living alone, marital status)…”

Section: Resultsmentioning

confidence: 99%

“…• Illness severity (Vlasnik et al, 2005; Schäfer-Keller et al, 2010; Baudrant-Boga et al, 2012; Zeber et al, 2013) (absence, reduction, disappearance or fluctuation of symptoms)…”

Section: Resultsmentioning

confidence: 99%

“…Patient determinants of non-adherence were often categorized according to the five dimensions of non-adherence proposed by WHO (Sabaté, 2003) or variations of these concepts (Baudrant-Boga et al, 2012): Social- and economic-related factors; Health system/health care team-related factors; Therapy-related factors; Condition-related factors, and Patient-related factors.…”

Section: Introductionmentioning

confidence: 99%

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Matching Adherence Interventions to Patient Determinants Using the Theoretical Domains Framework

et al. 2016

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Introduction: Despite much research, interventions to improve medication adherence report disappointing and inconsistent results. Tailored approaches that match interventions and patient determinants of non-adherence were seldom used in clinical trials. The presence of a multitude of theoretical frameworks and models to categorize interventions and patient determinants complicated the development of common categories shared by interventions and determinants. We retrieved potential interventions and patient determinants from published literature on medication adherence, matched them like locks and keys, and categorized them according to the Theoretical Domains Framework (TDF).Methods: We identified the most relevant literature reviews on interventions and determinants in a pragmatic literature search, extracted all interventions and determinants, grouped similar concepts to umbrella terms and assigned them to TDF categories. All steps were finalized in consensus discussion between the authors.Results: Sixteen articles (5 with determinants, 11 with interventions) were included for analysis. We extracted 103 interventions and 42 determinants that we divided in 26 modifiable and 16 unmodifiable determinants. All interventions and modifiable determinants were matched within 11 categories (Knowledge; Skills; Social/professional role and identity; Beliefs about capabilities; Beliefs about consequences; Intentions; Memory, Attention and decision processes; Environmental context and resources; Social influences; Emotion; and Behavioral regulation).Conclusion: In published trials on medication adherence, the congruence between interventions and determinants can be assessed with matching interventions to determinants. To be successful, interventions in medication adherence should target current modifiable determinants and be tailored to the unmodifiable determinants. Modifiable and unmodifiable determinants need to be assessed at inclusion of intervention studies to identify the patients most in need of an adherence intervention. Our matched categories may be useful to develop interventions in trials that investigate the effectiveness of adherence interventions.

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“…• Age (Vlasnik et al, 2005; Ingersoll and Cohen, 2008; Schäfer-Keller et al, 2010; Baudrant-Boga et al, 2012)…”

Section: Resultsmentioning

confidence: 99%

“…• Financial situation (Vlasnik et al, 2005; Baudrant-Boga et al, 2012) (socioeconomic status, lack of insurance, income, material resources)…”

Section: Resultsmentioning

confidence: 99%

“…• Housing situation/living situation (Vlasnik et al, 2005; Baudrant-Boga et al, 2012; Zeber et al, 2013) (lack of fixed address, living alone, marital status)…”

Section: Resultsmentioning

confidence: 99%

“…• Illness severity (Vlasnik et al, 2005; Schäfer-Keller et al, 2010; Baudrant-Boga et al, 2012; Zeber et al, 2013) (absence, reduction, disappearance or fluctuation of symptoms)…”

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Matching Adherence Interventions to Patient Determinants Using the Theoretical Domains Framework

et al. 2016

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Discordance between doctor and patient assessments and non-adherence to subcutaneous biological drugs

et al. 2019

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Exploring the factors influencing adherence to oral anticancer drugs in patients with digestive cancer: a qualitative study

Nizet

Touchefeu²,

Pécout³

et al. 2021

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Purpose The aim of this study was to explore the beliefs, perceptions and representations of patients in order to identify the determinants of oral anticancer drugs adherence and to take action in current practice to improve patient support in digestive oncology. Methods We constructed a semi-directed interview guide which aimed to explore the patient’s relationship with medication, their health history, their experiences at the time of the announcement of treatment, their confidence, their fears, their motivations to adhere to their treatment and the constraints linked to their treatment. The data were analysed and discussed using a thematic approach. Results Seventeen patients agreed to participate in the study. The median age was 60 years. Ten patients had colorectal cancer, 3 patients had hepatocellular carcinoma, 3 patients had gastrointestinal stromal tumour and 1 patient had neuroendocrine pancreatic tumour. We identified five categories of factors influencing adherence: demographic and socioeconomic, disease-related, treatment-related, care system-related, and patient representation and pathways’ factors. A majority of patients emphasised the importance of family support in the adherence process and the convenience of per os treatment compared to other intravenous treatments. However, several negative determinants emerged such as the toxicity of the treatment, fears of forgetting to take the medication, difficulties with the galenic formulation and negative beliefs of the family. Conclusion This study demonstrates the need to address the different dimensions of the patient in order to understand his or her behaviour with regard to adherence and to identify the levers for improvement.

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Penser autrement l’observance médicamenteuse : d’une posture injonctive à une alliance thérapeutique entre le patient et le soignant – Concepts et déterminants

Cited by 35 publications

References 65 publications

Matching Adherence Interventions to Patient Determinants Using the Theoretical Domains Framework

Matching Adherence Interventions to Patient Determinants Using the Theoretical Domains Framework

Discordance between doctor and patient assessments and non-adherence to subcutaneous biological drugs

Exploring the factors influencing adherence to oral anticancer drugs in patients with digestive cancer: a qualitative study

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