Penis and scrotum

Ro, Jae Y.; Kim, Kyu-Rae; Amin, Mahul B.; Ayala, Alberto G.

doi:10.1016/b978-0-323-01970-5.50017-8

Cited by 5 publications

(6 citation statements)

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“…Any patient with known cancer who develops priapism should be suspected of having metastatic disease. Other features include increased penile size, ulceration or palpable tumour nodules [48]. The corpus cavernosum is the most common site of metastases, but the penile skin, corpus spongiosum and mucosa of glans can be affected [49].…”

Section: Penismentioning

confidence: 99%

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Secondary neoplasms of the urinary system and male genital organs

et al. 2009

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BACKGROUND AND AIMS In this review we discuss those secondary tumours involving the urinary system and male genital organs that can pose differential diagnostic difficulties with primary lesions, and highlight morphological and ancillary features that could be helpful in reaching a proper assignment of primary origin. materials AND METHODS Based on MEDLINE database searches all reports of secondary tumours involving the urinary system (kidney and bladder) and male genital organs (prostate, testis and penis) were examined. RESULTS and discussion Involvement by a secondary tumour occurs either as a metastasis or by direct extension. Among non‐genitourinary primary sites, colorectal, pulmonary, skin (melanoma) and breast are the most common contributors. Secondary spread from a genitourinary site primary tumour to another genitourinary organ occurs most frequently between the prostate and urinary bladder, given the intimate topographic proximity of the two. The prognosis is very poor, as the secondary tumour usually occurs in patients with carcinoma in the late stages. Few secondary tumours have distinctive histological and immunohistochemical features, making it difficult to make the appropriate diagnosis. Hence, knowledge of the history and clinical setting are particularly important in these cases. CONCLUSION The urinary system and male genital organs are not common sites for secondary tumours. They often go either undiagnosed or misdiagnosed in the clinical follow‐up of patients with cancer. Accurate diagnosis is essential because of differing therapeutic approaches compared with a primary neoplasm.

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Section: Penismentioning

confidence: 99%

“…Many other primary sites are occasionally reported, including stomach and pulmonary. Tumour deposits might be seen in any part of the penis but the common finding is filling of the vascular spaces of the erectile tissue, and the tumour morphology will be typical of that seen in the primary tumour [48].…”

Section: Penismentioning

confidence: 99%

Secondary neoplasms of the urinary system and male genital organs

et al. 2009

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“…Gonococcal and other bacterial infections of these cysts, tracts, and openings as a consequence of sexual intercourse have occasionally been reported. The cysts are lined by pseudostratified columnar epithelium and may be unilocular or multilocular [19]. The canals are lined by stratified squamous epithelium that does not communicate with the urethra [20].…”

Section: Discussionmentioning

confidence: 99%

Clinical Study on Gonococcal Infection of the Penile Raphe

Fan

Zhang²,

Wei

et al. 2023

Urol Int

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Introduction: Gonococcal infection of the penile raphe is rarely encountered in the clinical setting. The study aimed to understand the incidence, sites, clinical manifestations, and treatment of gonococcal infection of the penile raphe. Methods: We enrolled men with gonococcal infection of the penile raphe and men with urethral gonorrhea from January 2010 to December 2021. All patients’ demographic data and clinical characteristics were recorded. All patients were treated with ceftriaxone. Incision and drainage were performed in patients with non-ruptured abscesses. Nodules and sinus tract-like lesions that did not resolve after 1 month of treatment were excised. Results: Among 2,736 men who presented with urethral gonorrhea from January 2010 to December 2021, 5 (0.18%) had accompanying gonococcal infection of the penile raphe. An additional two men presented with gonococcal infection of the penile raphe without urethritis. Thus, 7 (0.26%; confidence interval, 0.11–0.56%) of 2,738 men had urethral gonorrhea or gonococcal infection of the penile raphe confirmed both clinically and by laboratory testing. Lesions were present in the frenulum of the prepuce and at the median aspect, proximal end, distal end, and both the proximal and distal ends of the penile raphe. The lesions manifested as abscesses, ulcers, a nodule, and a nodule with a sinus-like lesion. All lesions exhibited tenderness. All seven patients were cured after treatment. Conclusion: Gonococcal infection of the penile raphe is a rare, atypical type of involvement of the male urogenital tract by Neisseria gonorrhoeae. It may be a local complication of urethral gonorrhea or an independent primary infection. The proximal end, distal end, and median aspect of the penile raphe can be infected by N. gonorrhoeae. Cutaneous lesions present as abscesses, ulcers, nodules, and sinus-like lesions. Ceftriaxone is effective, but sinus-like lesions require surgery.

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“…The glans is composed of epithelium, lamina propria, corpus spongiosum, tunica albuginea, and corpora cavernosa. The lamina propria is 1–3 mm thick and consists of a layer of loose connective tissue containing small vessels, lymphatics, nerves, and occasional Vater-Pacini corpuscles ( Ro et al, 2008 ). The male urethra (except where there is fossa navicularis), Littre’s ducts, Tyson’s ducts, paraurethral ducts, seminal vesicles, prostate, ampulla, vas deferens, and epididymis are lined with columnar epithelium that is susceptible to gonococcal infections ( Harkness, 1948 ; Subramanian, 1981 ).…”

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confidence: 99%

Gonococcal Infection of the Glans Skin, a Rare Local Complication of Gonorrhea: A Clinical Study of 13 Cases

et al. 2023

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The study aimed to understand the incidence, site, skin lesion manifestations, and treatment of gonococcal infection of the glans skin. We enrolled men with gonococcal infection of the glans skin and men with gonococcal urethritis from January 2014 to February 2020. Demographic data, site of onset, and skin lesion manifestations were recorded for all patients. Ceftriaxone (1 g) was injected intramuscularly once daily for 5 days in patients with lesions comprising abscesses or nodules. A single dose of ceftriaxone (1 g) was injected intramuscularly in patients with pustules. Incision and drainage were performed in patients with nonruptured abscesses. Thirteen patients had gonococcal infection of the glans skin (0.65%; 95% confidence interval = [0.30, 1.01]) among 1,989 patients with gonococcal urethritis. Mean age was 35.48 ± 2.37 (range = 26–45) years. Nonmarital sexual behavior patterns were genital–genital in eight patients (61.54%) and genital–oral in five patients (38.46%). All skin lesions occurred on the ventral side of the glans. Eleven patients (84.62%) had a single lesion and two (15.38%) had multiple lesions. The lesions manifested as abscesses in five patients (38.46%), nodules in five patients (38.46%), and pustules in three patients (23.08%). All lesions exhibited tenderness. All 13 patients were cured after treatment. The study shows that gonococcal infection of the glans skin is a rare local complication of gonorrhea. Lesions often occur on the ventral side of the glans, presenting as abscesses, nodules, and pustules. Ceftriaxone treatment was effective for gonococcal infection of the glans skin.

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Penis and scrotum

Cited by 5 publications

References 438 publications

Secondary neoplasms of the urinary system and male genital organs

Secondary neoplasms of the urinary system and male genital organs

Clinical Study on Gonococcal Infection of the Penile Raphe

Gonococcal Infection of the Glans Skin, a Rare Local Complication of Gonorrhea: A Clinical Study of 13 Cases

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