Penile-preserving surgery for primary urothelial carcinoma of male urethra

Tai, Hao-Ping; Yin, Jue-Hawn; Huang, Zhon-Min; Tsao, Tang‐Yi

doi:10.1016/j.urols.2015.03.001

Cited by 2 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Extensive radical surgical removal of the tumor is currently regarded as the mainstay of management. However, small tumors of the urethra have been proven to be able to be treated with transurethral resection and penile preserving surgery [19][20][21]. A level one evidence could not be established to support the efficacy of chemotherapy and radiotherapy in the management of UC of the urethra due to the rarity of such conditions.…”

Section: Discussionmentioning

confidence: 99%

A Primary Urothelial Carcinoma Presenting as a Mid-Bulbar Urethral Stricture in a 30-Year-Old Male

Alghafees

Seyam

Altaweel

et al. 2021

Cureus

View full text Add to dashboard Cite

The bulbar urethra is the most common site of anterior urethral strictures. In this case report, we present a 30-year-old male who was referred to us as a case of mid-bulbar urethral stricture. Urethroplasty was booked and a papillary lesion was found on routine diagnostic cystoscopy. An open biopsy was taken which showed invasive high-grade papillary urothelial carcinoma with squamous differentiation. This case is rare in terms of a young age of incidence, a lack of risk factors, an absence of suspicious symptoms, and a short duration of signs and symptoms. Urologists should consider workup for malignancy even in young patients who present with an idiopathic urethral stricture and a short duration of symptoms.

show abstract

Section: Discussionmentioning

confidence: 99%

A Primary Urothelial Carcinoma Presenting as a Mid-Bulbar Urethral Stricture in a 30-Year-Old Male

Alghafees

Seyam

Altaweel

et al. 2021

Cureus

View full text Add to dashboard Cite

show abstract

“…This is one of the reasons why it is impossible to obtain the correct urine flow conditions. Histological examination allows to obtain the exact dimensions and volume content of the tissues that are a part of such organ as urethra [27][28][29][30]. These studies also allow to determine the real state of the tissue (inflammatory, fibrosis or normal), which affects different, non-linear mechanical properties and conditions of the urethra structures reconstruction and change the distribution of strain fields [31].…”

Section: Introductionmentioning

confidence: 99%

Numerical Analysis of Deformation and Flow in the Proximal Area of the Urethra

Rudyk

Malinowski

Mackiewicz

et al. 2020

International Journal of Applied Mechanics and Engineering

View full text Add to dashboard Cite

Pathological conditions of a male urethra, including fibrosis, have a mechanical background along the entire length of the urethra. They may be caused by excessive deformation of the urethra locally or globally. The condition of prolonged overload causes abnormal tissue remodelling and, consequently, the formation of a thick layer of scar tissue differentiated from the connective tissue of the urethra. This tissue, which has higher mechanical properties, is not highly deformable and therefore, causes a decrease in the diameter of the urethra, which results in conditions that disturb the natural flow of urine. In this paper, it was decided to determine the deformation conditions in the proximal part of the urethra. The study was conducted in three main stages. Transverse sections of the animal urethral tissues were prepared in order to examine mechanical properties and perform histological examinations. On the basis of these examinations, material models which fitted best for the experimental results were sought. Material constants of the Mooney-Rivlin material model with the best fit ratio were determined for further research. On the basis of histological photographs, a geometrical and numerical model of the urethra was developed. The urethra was tested in a flat state of deformation. The strain and stress fields of the Caucha tensor were examined. The methodology of testing the dynamics of the urine flow in the highly deformable urethra was proposed. This is important for the analysis of the influence of at excessive pressure on pathological tissue remodelling leading to fibrosis.

show abstract

Penile-preserving surgery for primary urothelial carcinoma of male urethra

Cited by 2 publications

References 5 publications

A Primary Urothelial Carcinoma Presenting as a Mid-Bulbar Urethral Stricture in a 30-Year-Old Male

A Primary Urothelial Carcinoma Presenting as a Mid-Bulbar Urethral Stricture in a 30-Year-Old Male

Numerical Analysis of Deformation and Flow in the Proximal Area of the Urethra

Contact Info

Product

Resources

About