Penile Preservation Surgery in a Case of Extramammary Paget's Disease Involving the Glans Penis and Distal Urethra

Fujisawa, Yasuhiro; Nakamura, Yasuhiro; Takahashi, Takenori; Kawachi, Yasuhiro; Otsuka, Fujio

doi:10.1111/j.1524-4725.2008.34154.x

Cited by 6 publications

(5 citation statements)

References 32 publications

(67 reference statements)

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“…It mostly occurs in sites with abundant apocrine sweat glands, such as scrotum, penis, vulva, perianal, and so on [ 2 , 3 ]. EMPD of the scrotum and penis, also known as scrotal eczema-like carcinoma, is a relatively rare skin malignant tumor, accounting for only 6.5% of all Paget’s disease [ 4 , 5 ]. EMPD of the scrotal and penile was first proposed by Crocker in 1889 [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Extramammary Paget’s Disease of the Scrotal and Penile: A Case Report and Review of the Literature

Yang,

Lin,

Gao

et al. 2024

Urol Int

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Introduction: Extramammary Paget's Disease of the scrotum and penis is a relatively rare cutaneous malignant tumor. At present, its pathogenesis, clinical and pathological characteristics are not very clear. There is controversial regarding surgical margin width to decrease the high recurrence rate. This paper aims to report the case and review the literature of Extramammary Paget's Disease of scrotum and penis. Case Presentation: We presented the case of a 74-year-old male patient with the patchy erythema and pruritus in the perineum who was admitted to our department. Biopsy of the large plaque revealed Paget disease. Under the condition of ensuring negative surgical margins by rapid frozen pathology, a wide local excision of the lesion, bilateral orchiectomy and adnexectomy were performed on the patient. Pathology revealed that many scattered vacuolated Paget cells were observed in the epidermal layer, and the diagnosis was Paget's disease of the scrotum and penis. The 2cm outside the skin lesion was used as the initial surgical margin and free skin flap transplantation was used to repair the surgical wound. The patient recovered well and was discharged one week after surgery. Conclusion: Currently, histopathologic biopsy is the most important diagnostic method for EMPD. Once confirmed, for patients eligible for surgical intervention, wide local excision of the lesion and rapid intraoperative frozen pathological examination should be performed as soon as possible. The skin flap transplantation is the first choice for the repair of large-scale wound after surgery.

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Section: Introductionmentioning

confidence: 99%

Extramammary Paget’s Disease of the Scrotal and Penile: A Case Report and Review of the Literature

Yang,

Lin,

Gao

et al. 2024

Urol Int

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“…The male genital organ is composed of three erectile cylinders: the bilateral corpus cavernosus (CC) and the underlying corpus spongiosum (CS) (Hsu, 2006;Sam & LaGrange, 2022). The bilateral corpus cavernous (CC) run side by side and together with the underlying corpus spongiosum, form the body of the penis (Fujisawa et al, 2008;Sam & LaGrange, 2022). The top of the CC is covered with glans cap (Hsieh et al, 2012;Kureel et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Detailed Anatomy of the Corpora-Glans Ligament via the P45 Plastination Method

Jiang

Gilmore

et al. 2023

Int. J. Morphol.

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The corporo-glans ligament is the ligament connecting the corpus cavernosum and the glans of the penis. The anatomical description of the corporo-glans ligaments shape is still uncertain, this knowledge affects penile reconstructive procedures. The anatomy of the corporo-glans ligament was analyzed and recorded via observing sagittal sections of 10 different penile P45 plastination sections. According to the P45 plastination sections, the corporo-glans junction displayed a fibrous tissue band connecting the distal ends of the two corpus cavernous (CC) with the glans penis (GP). The fibrous band was a round-obtuse shape and ran deep into the glans of the penis and occupied about 2/3 of the whole GP. The original end was laid in a socket embedded in the GP. The density of the fibers of the ligament at the original end close to the tunica albuginea was less than that of the other parts. The fibers originating from the tunica albuginea, directly extended to the blind end of the two CC, covering the distal end of the two CC.

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“…However, penectomy spoils function and morphology. The anatomy of the penis as illustrated (Fig. a) contains two corpora cavernosa on the dorsal aspect of the penis and the corpus spongiosum on the ventral aspect.…”

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confidence: 99%

“…According to their anatomic findings, an intraepithelial tumor involving the glans penis can be removed by excision from the elastic fiber layer. The resulting skin defect on the glans penis and the urethral mucosa can be covered by a free skin graft . A tube graft can be used for reconstruction of the urethral carcinoma in situ , which is more aesthetic, natural, and penis‐sparing than covering by a free skin graft, but the technique is complicated and there is still a risk of urethral stricture after surgery.…”

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confidence: 99%

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Penile preservation surgery in a case of erythroplasia of Queyrat involving the glans penis and distal urethra

et al. 2013

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Penile Preservation Surgery in a Case of Extramammary Paget's Disease Involving the Glans Penis and Distal Urethra

Cited by 6 publications

References 32 publications

Extramammary Paget’s Disease of the Scrotal and Penile: A Case Report and Review of the Literature

Extramammary Paget’s Disease of the Scrotal and Penile: A Case Report and Review of the Literature

Detailed Anatomy of the Corpora-Glans Ligament via the P45 Plastination Method

Penile preservation surgery in a case of erythroplasia of Queyrat involving the glans penis and distal urethra

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