Penile lesion in a dialysis patient: Time to get an X‐ray

Koratala, Abhilash; Chamarthi, Gajapathiraju

doi:10.1002/ccr3.1669

Cited by 3 publications

(3 citation statements)

References 3 publications

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“…The delayed diagnosis caused by clinicians' insufficient understanding of calciphylaxis contributes to this serious illness condition. The predilection sites of calciphylaxis are soft and fatty tissues, for instance, the abdomen, buttocks and thighs [1,4], although necrosis of the extremities such as fingers [15] and penises [16,17] is also constantly reported. Davis et al conducted a literature review and found that obesity was identified as a risk factor in six of the eight studies reviewed [18].…”

Section: Discussionmentioning

confidence: 99%

Risk factors for calciphylaxis in Chinese hemodialysis patients: a matched case-control study

et al. 2021

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Introduction: Calciphylaxis is a rare but potentially fatal disease commonly occurred in dialysis patients. Despite some previous studies on risk factors for calciphylaxis, there is still a lack of data from Chinese population. Methods: The retrospective matched case-control study about calciphylaxis was performed in Zhongda Hospital affiliated to Southeast University. The case group involved 20 hemodialysis patients who were newly diagnosed with calciphylaxis from October 2017 to December 2018. The 40 noncalciphylaxis patients undergoing dialysis with the same age and duration of dialysis were randomly selected as controls. Results: Most of calciphylaxis patients were male and elderly, while overweight people were more susceptible to the disease. Although incidence of secondary hyperparathyroidism was higher in calciphylaxis patients, the differences in duration of elevated serum intact parathyroid hormone (iPTH) and its highest value did not reach statistical significance compared with controls. No significant difference in warfarin therapy was discernible between two groups. The univariate regression analysis indicated that male, score of use of activated vitamin D and its analogues, corrected serum calcium level, serum phosphate, Ca Â P product, iPTH, albumin, and alkaline phosphatase (ALP) level were significantly associated with calciphylaxis. Elevated levels of serum phosphate (OR 4.584, p ¼ 0.027) and ALP (OR 1.179, p ¼ 0.036), decreased level of serum albumin (OR 1.330, p ¼ 0.013) were independent risk factors after multivariate analysis. Conclusion: This is the first report of risk factors associated with calciphylaxis in China. Increased levels of serum phosphate and ALP, decreased level of serum albumin were vital high-risk factors for calciphylaxis in Chinese hemodialysis population.

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Section: Discussionmentioning

confidence: 99%

Risk factors for calciphylaxis in Chinese hemodialysis patients: a matched case-control study

et al. 2021

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“…Diagnosis is determined after reviewing the patient's health history and a focused wound assessment finding of classic painful ulcerated lesions that are covered by a black eschar. While some healthcare providers still use skin biopsy as a diagnostic tool, it is no longer the gold standard for diagnosing penile calciphylaxis 8,9. In fact, there is some debate about its use.…”

Section: Diagnosismentioning

confidence: 99%

“…While some healthcare providers still use skin biopsy as a diagnostic tool, it is no longer the gold standard for diagnosing penile calciphylaxis. 8,9 In fact, there is some debate about its use.…”

Section: Wwwnursing2021commentioning

confidence: 99%