Penile Invasive Squamous Cell Carcinoma Arising on Bowenoid Papulosis – Case Report

Abstract

Penile squamous cell carcinoma occurs more frequently after 50 years in uncircumcised men, usually with phimosis. It can develop on the following precancerous lesions: erythroplasia of Queyrat, penile cutaneous horn, genital lichen sclerosus, leukoplakia, pseudoepitheliomatous keratotic and micaceous balanitis, Buschke-Lowenstein condylomatosis, Bowenoid papulosis. It has poor prognosis due to invasion depth and increased risk of metastasis.We present the case of a 56-year-old man who developed an invasive penile squamous-cell carcinoma after a six-year history of Bowenoid papulosis. Circumcision was performed with very good postoperative evolution. The patient has been followed-up for three years with no complications.In conclusion, persistent high-risk human papillomavirus infection in a smoker, uncircumcised man can cause squamous cell carcinoma.