Penile Cancer

Tsoukalas, Nikolaos; Tsapakidis, Konstantinos; Kyrgias, George; Tolia, Maria

doi:10.1007/978-3-030-16245-0_30

Cited by 1 publication

(3 citation statements)

References 23 publications

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“…Squamous cell carcinoma (SCC) accounts for over 95% of penile cancers. 1 Closely-related conditions include Bowen's disease and Erythroplasia of Queyrat, both of which tend to progress to invasive disease, whereas bowenoid papulosis does not have malignant potential. 2 Risk factors for penile SCC include uncircumcised males, human papillomavirus (HPV), immunosuppression, chronic infection, phimosis, poor hygiene, multiple sexual partners, and tobacco exposure.…”

Section: Introductionmentioning

confidence: 99%

“…2,3 Diagnosis is delayed in up to 50% of patients due to fear, carelessness, and embarrassment. 1,4 This delay often leads to detection of advanced disease, as one-third of patients have progressed beyond organconfined disease at the time of diagnosis. 4 The most common site of metastasis of penile SCC is regional superficial inguinal lymph nodes and then sequentially the deep inguinal and pelvic lymph nodes before visceral spread.…”

Section: Introductionmentioning

confidence: 99%

“…4 The most common site of metastasis of penile SCC is regional superficial inguinal lymph nodes and then sequentially the deep inguinal and pelvic lymph nodes before visceral spread. 1 The staging of SCC based on lymph node involvement is a studied predictor of survivability, with inguinal lymph nodes having approximately 80% survival rates, while pelvic lymph nodes have 0-33%. 5 Primary presentation of distant metastasis of penile SCC is rare and occurs late in the course of the disease.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Primary Penile Squamous Cell Carcinoma in a Patient with Metastatic Adenocarcinoma of Colon to Liver: A Case Report

Dalton

Son²,

Flemming

et al. 2022

EMJ Urol

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Penile squamous cell carcinoma (SCC) is a rare malignancy associated with human papillomavirus and immunosuppression. If not detected early in its course, local invasion and metastasis to distant regions often occurs. Colorectal adenocarcinoma (CRAC) is the third most common malignancy worldwide. Many familial genetic mutations are associated with CRAC; however, co-presentation with penile SCC has not been established in literature. The authors present a case in which a patient presenting with a primary diagnosis of penile SCC was found to have distant liver metastases due to a previously unknown recurrence of CRAC. The authors conclude that primary penile cancer with subsequent metastatic colon adenocarcinoma is possible in patients with unknown genetic predisposition.

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Section: Introductionmentioning

confidence: 99%