Penile acrochordon: An unusual site of presentation- A case report and review of the literature

Unusually Large Skin Tag of Labium Majus

“…Skin tags are harmless and typically painless. They are not expected to change in size over time [5]. However, our patient described a growth during the 3 years.…”

“…Skin tags have been reported in association with aging, obesity, diabetes mellitus, impaired carbohydrate or lipid metabolism, liver enzyme abnormalities, hypertension, acromegaly, Crohn's disease, colonic polyps [10]- [12]. Rarely, they can be associated with polycystic ovary syndrome (PCOS) [5]. It is suggested that the origin is most probably from a regressing nevus [13].…”

Androgen Receptor-Positive Penile Acrochordon: A Case Report

“…Skin tags can occur at any age. They are typically asymptomatic, usually smaller than 5 mm in length, and rarely exceed 1 cm [ 3 ]. Microscopically, an acrochordon consists of a fibrovascular core, sometimes also with fat cells, covered by an unremarkable epidermis or an acanthotic, flattened, or frond-like epithelium [ 4 ].…”

“…Skin tags may be an important marker for the presence of type II diabetes mellitus [ 5 ]. The incidence is increased in patients with obesity, hyperlipidemia, insulin resistance, and acromegaly; therefore, hormonal factors are also considered [ 3 ]. However, unlike the literature, in our case, the lesion grew rapidly along with body development during puberty and reached a size approximately 5-10 times larger than the initial size.…”

“…They may be associated with diabetes, obesity, hyperlipidemia, insulin resistance, acromegaly, and trauma [ 2 ]. Physical examination is usually sufficient for diagnosis, but in rare cases, histopathological examination may be necessary due to an unusual site of presentation and no underlying causes [ 3 ]. To the best of our knowledge, in English literature, we report the first case of an androgen receptor-positive penile acrochordon located on the glans penis, which showed rapid growth along with body development during puberty.…”