Penicillins, Cephalosporins, and Other β-Lactam Antibiotics

Vilvanathan, Saranya

doi:10.1007/978-981-33-6009-9_54

Cited by 2 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To assess Cef in a pharmaceutical preparation in the form of tablets, a weight of 0.1032 g of the preparation was collected and dissolved in 100 ml of dimethyl sulfoxide, then the solution was filtered and three concentrations were extracted from the filter. It was successful suggested methods of estimating (Cef) in various commercial tablets [16][17][18][19][20].…”

Section: Methodsmentioning

confidence: 99%

Determination of cefdinir in pharmaceutical preparations by oxidative conjugation method

Raffat

Rashid

2022

ijhs

View full text Add to dashboard Cite

In order to detect of Cefidinir (CEF) in its pure form and in its pharmaceuticals have been devised the proposed methods were: (I) oxidative conjugation in an alkaline medium between (CEF) and regent "p-Aminobanzoicacid" to produce an intense yellow colored product, (II) oxidative conjugation between (CEF) and 2,4-Dipyridin in an alkaline medium to generate a bright golden yellow colored product. Absorption of the reagent p-Aminobanzoicacid is 0.589 in 467nm, and highest absorption of the reagent 2,4-Dipyridin is 0.851 in724 nm, with molar absorptivity of 4.99×104 Lmol.cm, and 9.25×104 Lmol.cm. The limits of detection (LOD) for p-Aminobanzoicacid" and 2,4-Dipyridin were found to be 0.033 g/ml, and 0.007 respectively. In both its pure form and pharmaceutical forms, the proposed approach was successful in estimating "This drug.."

show abstract

Section: Methodsmentioning

confidence: 99%

Determination of cefdinir in pharmaceutical preparations by oxidative conjugation method

Raffat

Rashid

2022

ijhs

View full text Add to dashboard Cite

show abstract

“…Cefdinir (Fig. 1) is an antibacterial agent that can be taken orally [1], is an antibiotic of the third generation that is resistant to Gram-negative bacteria as well as some Gram-positive bacteria [2], it's used to treat urinary tract infections, acute hepatitis, rhinosinusitis, and pharyngitis (tonsillitis) [3] Several methods have been proposed for determination of this drug, such as HPLC [4,5], TLC [6], HPTLC [7], UV-Voltammetry [8,9]. Spectrophotometry [10,11], UV-Vis.…”

Section: Introductionmentioning

confidence: 99%

“…Figure (3): Effect the volum 4-Chlorobanzaldehayde of on product3.1.2. Effect of base volume:To see how increasing volumes of sodium hydroxide solution with an initial concentration of 1M affect the resultant absorption values, the optimal added volumes were found to be 0.5 ml[25,26], as shown in figure(4).…”

mentioning

confidence: 99%

Spectrophotometric determination of cefdinir in the ‎pharmaceutical preparations

Raffat

Rashid

2022

ijhs

View full text Add to dashboard Cite

Two simple, quick, and sensitive techniques for spectrophotometric determination of Cefdinir (Cef) in ‎its pure form and pharmaceutical formulations have been devised. The proposed methods were: (I) synthesis of a ‎Schiff's base between Cefdinir and 4-Chlorobanzaldehayde reagent in an alkaline medium to produce a yellow-‎colored product, (II) diazotization and coupling between (Cef) and Orthophenylenediamime in an alkaline ‎medium to produce an intense yellow colored product. The highest absorptions were measured at 0.568 with the ‎reagent 4-Chlorobanzaldehayde and 0.871 with the reagent Orthophenylenediamime. Beer's Law holds true for ‎‎4-Chlorobanzaldehayde and Orthophenylenediamime at concentrations of (10-200g/ml), (10-135g/ml), ‎respectively, with molar absorptivity of ‎‏105×1.35‏‎ Lmol.cm and 1.66×105 Lmol.cm. The limits of detection ‎‎(LOD) for 4-Chlorobanzaldehayde and Orthophenylenediamime were found to be‏0.021 ‏g/ml and 0.022 g/ml, ‎respectively. The proposed method proved successful in estimating "This medication" in both its pure form and ‎in pharmaceutical formulations.

show abstract

Penicillins, Cephalosporins, and Other β-Lactam Antibiotics

Cited by 2 publications

References 0 publications

Determination of cefdinir in pharmaceutical preparations by oxidative conjugation method

Determination of cefdinir in pharmaceutical preparations by oxidative conjugation method

Spectrophotometric determination of cefdinir in the ‎pharmaceutical preparations

Contact Info

Product

Resources

About