Penicillin Treatment of Acute Syphilitic Nephrosis and Iritis

The Nephrotic Syndrome in Secondary Syphilis

“…Despite the rarity of the nephrotic syndrome in secondary syphilis, enough case reports have appeared in the literature to well document its existence (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Although most cases seemed to have responded to therapy, in a number of instances spontaneous remission occurred prior to the institution of specific therapy (2,4,7,10,12), as, indeed, seemed to have happened in the present case.…”

“…S EVERAL CASES of the nephrotic syndrome associated with active syphilitic infection have been reported in the past (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Because of the self-limited nature of this illness, however, there have been few reports containing histologic descriptions of the kidney during the active phase of the nephrotic syndrome.…”