Penggunaan Antibiotik Secara Bijak Untuk Mengurangi Resistensi Antibiotik, Studi Intervensi di Bagian Kesehatan Anak RS Dr. Kariadi

Farida, Helmia; Herawati, Herawati; Hapsari, MM Deah; Notoatmodjo, Harsoyo; Hardian, Hardian

doi:10.14238/sp10.1.2008.34-41

Cited by 10 publications

(13 citation statements)

References 1 publication

(1 reference statement)

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“…A total of 13 reports reported data on the effect of AMS interventions, of which 11 in hospitals, 23,28,31,33,47,[86][87][88][89][90][91] 1 in primary care, 92 and 1 in community pharmacies 93 (Table 2). Twelve reports used a pre-post design, and one was a randomized controlled trial.…”

Section: Antibiotic Stewardship Interventionsmentioning

confidence: 99%

“…23,31,47,86,88,90,91 Studies that evaluated education and/or training interventions (5 reports) reported mixed effects on antibiotic consumption and prescribing appropriateness. 31,[87][88][89]92 The one study that evaluated antibiotic restriction with pre-approval found that consumption of restricted antibiotics decreased and of unrestricted narrow-spectrum antibiotics increased. 28 The one randomised study that evaluated the effect of a pharmacist counselling session of outpatient antibiotic users in community pharmacies found that self-reported antibiotic adherence was 311 significantly higher in the intervention group compared to the control group.…”

Section: Antibiotic Stewardship Interventionsmentioning

confidence: 99%

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Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

Limato

Lazarus

Dernison

et al. 2022

Preprint

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Introduction A major driver of antimicrobial resistance (AMR) and poor clinical outcomes is suboptimal antibiotic use, although data are lacking in low-resource settings. We reviewed studies on systemic antibiotic use (WHO ATC/DDD category J01) for human health in Indonesia, and synthesized available evidence to identify opportunities for intervention. Methods We systematically searched five international and national databases for eligible peer-reviewed articles, in English and Indonesian, published between 1 January 2000 and 1 June 2021 including: 1) antibiotic consumption; 2) prescribing appropriateness; 3) antimicrobial stewardship (AMS); 4) perceptions among consumers and providers. Two independent reviewers included studies and extracted data. Study-level data were summarized using random-effects model meta-analysis for consumption and prescribing appropriateness, effect direction analysis for AMS interventions, and qualitative synthesis for perception surveys. (PROSPERO CRD42019134641) Results Of 9323 search hits, we included 100 reports on antibiotic consumption (20), prescribing appropriateness (49), AMS (13), and/or perception (25) (8 categorized in >1 domain). The pooled estimate of overall antibiotic consumption was 110.1 DDD/100 patient-days (95%CI98.5-121.6), with ceftriaxone, ampicillin and levofloxacin being most consumed. Pooled estimates for overall appropriate prescribing (according to Gyssens method) were 33.5% (95%CI18.1-53.4%) in hospitals and 49.4% (95%CI23.7-75.4%) in primary care. Pooled estimates for appropriate prescribing (according to reference guidelines) were, in hospitals, 99.7% (95%CI97.4-100%) for indication, 84.9% (95%CI38.5-98.0%) for drug choice, and 6.1% (95%CI0.2-63.2%) for overall appropriateness, and, in primary care, 98.9% (95%CI60.9-100%) for indication, 82.6% (95%CI50.5%-95.7%) for drug choice and 10.5% (95%CI0.8-62.6%) for overall appropriateness. The few AMS intervention studies conducted to date suggested potential to reduce antibiotic consumption and improve prescribing appropriateness. Key themes identified in perception surveys were lack of antibiotic knowledge among consumers and non-prescription antibiotic self-medication. Conclusions Context-specific strategies are urgently needed to improve rational antibiotic use in Indonesian hospitals and communities, with critical evidence gaps concerning private and informal health providers.

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Section: Antibiotic Stewardship Interventionsmentioning

confidence: 99%

Section: Antibiotic Stewardship Interventionsmentioning

confidence: 99%

Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

Limato

Lazarus

Dernison

et al. 2022

Preprint

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“…Di sisi lain, dampak dari resistensi bakteri ini ialah kegagalan dalam pengobatan penyakit dengan terapi antibiotik. Hal ini tentunya akan sangat merugikan dan berampak buruk bagi kesehatan masyarakat di masa depan (Farida, et. al., 2016).…”

Section: Gambar 2 Proses Diskusi Teararah (Fgd)unclassified

Edukasi bahaya resistensi bakteri akibat penggunaan antibiotik yang tidak rasional kepada masyarakat Desa Air Salobar

Yunita

Sukmawati

2021

Indones. Berdaya.

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Abstrak: Masalah resistensi bakteri terhadap antibiotik tidak hanya terjadi di Indonesia tetapi juga secara global dan menjadi satu persoalan yang cukup rumit dan harus segera diatasi bersama-sama. Di masyarakat, kerap kali antibiotik dibeli tanpa penjelasan dan resep dokter. Masyarakat juga kerap membeli antibiotik dengan resep yang pernah diperoleh sebelumnya, bahkan langsung mengonsumsi antibiotik untuk penyakit ringan yang penanganannya tidak selalu membutuhkan antibiotik seperti demam, batuk dan pilek. Tujuan dari kegiatan pengabdian masyarakat ini ialah memberikan edukasi mengenai bahaya resistensi bakteri akibat penggunaan antibiotik yang tidak rasional kepada masyarakat desa Air salobar kecamatan Nusaniwe Ambon. Metode yang digunakan pada kegiatan ini adalah metode ceramah dengan memberikan materi mengenai bahaya resistensi bakteri akibat penggunaan antibiotik yang tidak rasional secara langsung. Hasil dari kegiatan pengabdian yang telah dilakukan menunjukkan bahwa masyarakat desa Air Salobar sangat antusias terhadap kegiatan yang dilaksanakan. Hal tersebut ditandai dengan antusiasnya, warga dalam menerima materi edukasi. Selain itu, warga yang hadir dalam kegiatan ini aktif memberikan respon timbal balik terhadap pemateri dengan cara memberikan pertanyaan-pertanyaan mengenai penyebab dan efek dari resistensi bakteri terhadap antibiotik. Abstract: Bacterial resistance issue does not only occur in Indonesia but also globally and becomes a quite complex problem and must be addressed together. Commonly, antibiotics are often purchased without a doctor’s explanation and prescription. People tend to buy antibiotics with prescriptions that have been obtained before, even directly consuming antibiotics for minor ailments whose treatment does not always require antibiotics such as fever, cough and cold. The purpose of this activity was to educate the community on the dangers of bacterial resistance due to irrational use of antibiotics to the community of Air Salobar Village, Nusaniwe district, Ambon. The method used was a lecture method by providing material on the dangers of bacterial resistance due to irrational use of antibiotics directly. The results showed that the residents of Air Salobar village are very enthusiastic about the community service activity carried out. This was indicated by the enthusiasm of the residents in receiving educational materials. Apart from that, the residents who attended this activity actively gave a reciprocal response to the presenters by asking questions about the causes and effects of bacterial resistance to antibiotics.

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“…This should not occur in inpatients who can be monitored 24 hours and the availability of a more complete diagnostic tool. 17 National health insurance services are carried out by conducting cooperation agreements between BPJS and health facilities that exist throughout Indonesia. 20 Analysis of antibiotic financing in hospitals has an effect on the duration of administration of drugs, the amount of drug administration, profit margins, services.…”

Section: Conclussionmentioning

confidence: 99%

Patient safety: antibiotics prescription review in pediatric patient

Faizin

Kusumawati

Habib

2019

JMMR

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Penggunaan Antibiotik Secara Bijak Untuk Mengurangi Resistensi Antibiotik, Studi Intervensi di Bagian Kesehatan Anak RS Dr. Kariadi

Cited by 10 publications

References 1 publication

Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

Edukasi bahaya resistensi bakteri akibat penggunaan antibiotik yang tidak rasional kepada masyarakat Desa Air Salobar

Patient safety: antibiotics prescription review in pediatric patient

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