PENGARUH KOMBINASI EKSTRAK DAUN ASHITABA (Angelica keiskei Ito.) DAN DAUN SUKUN (Artocarpus communis) TERHADAP KADAR GLUKOSA DAN KOLESTEROL SECARA IN VITRO MENGGUNAKAN METODE FOTOMETRI

Luhurningtyas, Fania Putri; Hasani, Nova; Aprilliana, Melati; Saputra, Deny; Prayasanti, Dewi

doi:10.33751/jf.v9i1.1260

Cited by 2 publications

(4 citation statements)

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“…Metode Lieberman-Burchad digunakan untuk mengkomplekskan kolesterol menghasilkan kompleks berwarna hijau. Metode ini khusus untuk menganalisis senyawa golongan steroid dimana kolesterol merupakan bagian dari golongan steroid tersebut (Luhurningtyas et al, 2019). Menurut (Anggraini& Kusuma, 2019) bahwa saat reaksi berlangsung, di dalam sistem tidak boleh mengandung air karena keberadaan air akan mengganggu jalannya reaksi dan membuat senyawa produk menjadi mudah pecah.…”

Section: Pendahuluanunclassified

“…Ekstrak etanol kulit mentimun (Cucumis sativus L.) ditentukan kemampuan penurunan kolesterolnya menggunakan metode Lieberman-burchad dan diukur menggunakan spektrofotometer UV-Visibel. Metode ini bersifat spesifik dalam mengukur senyawa kolesterol yang termasuk dalam salah satu golongan steroid (Luhurningtyas et al, 2019). Kolesterol memiliki sifat fotodegradasi sehingga apabila terpapar cahaya, sifatnya menjadi tidak stabil sehingga berubah menjadi kolestenon (Gambar 1).…”

Section: Hasil Dan Pembahasanunclassified

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LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

Sumarni

Sadino²,

Sumiwi

2022

JFSP

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Kersen (Muntingia calabura L.) is known as a plant that is often used as a tree to absorb air pollution and shade on the roadside. Low economic value and public knowledge about the benefits of cherry as a medicinal and food ingredient is still minimal. The part that can be used as a medicinal ingredient comes from cherry leaves. The purpose of this review article is to provide information related to the chemical content and pharmacological activity of cherry leaves that can treat various diseases. The method used in making this article review is a literature study. The literature sources in this article review were obtained from national journals and international journals published in the last 10 years (2010-2020), which were carried out online through the search engines Google Scholar, Pubmed, and NCBI, using the keywords "Kersen leaves", "Activities cherry leaf”, “Pharmacological activity of Muntingia calabura”, “Chemical content of cherry leaf”, “Muntingia calabura L.”. Journals that enter the inclusion criteria are national and international journals that discuss the pharmacological activity and chemical content of cherry leaves, journals published in the last 10 years (2010-2020), and journals in full text. The chemical constituents contained in cherry leaves are flavonoids, saponins, tannins, and terpenoids. Cherry leaves are scientifically proven to have several pharmacological activities as antidiabetic, antioxidant, antibacterial, anthelmintic, antihyperlipidemic, and anti-inflammatory.

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Section: Pendahuluanunclassified

Section: Hasil Dan Pembahasanunclassified

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

Sumarni

Sadino²,

Sumiwi

2022

JFSP

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Section: Pendahuluanunclassified

Section: Hasil Dan Pembahasanunclassified

The Potency of Cucumber (Cucumis Sativus L.) Peel Extract as Anticholesterol

Putri¹,

Anggraini²

2022

JFSP

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The liver has a very important role in the human body. However, these organ tissues are also very susceptible to be tissue damage. Fatty liver disease (steatosis) is a disease caused by high cholesterol. Physically, cholesterol is a yellowish subtance, lumps like wax, and is an arrangement of steroid groups. Non-alcoholic steatohepatitis (NASH) occurs due to excess cholesterol levels in the liver. Liver function can be affected as a result of liver damage. So, a hepatoprotector is needed. The flavonoid content of cucumber skin has potential as an anticholesterol. The purpose of this research is to analyze the ability of the ethanol extract of cucumber peel (Cucumis sativus L.) as a cholesterol lowering agents as indicated by the EC50 value. Maceration extraction method used in this study using 96% ethanol as solvent. Qualitative analysis of ethanolic extract of cucumber peel is known to have flavonoids, steroids, alkaloids as indicated by the appearance of color changes, and saponins which are indicated by the appearance of foam. Lieberman-burchad reagent was used for quantitative analysis of anticholesterol using a UV-Visible spectrophotometer. The analysis was carried out at a maximum wavelength of 665,0 nm with an incubation time of 15 minutes. The concentration variations of the extract used were between 25-150 with a range of 25 ppm. The results showed that the ethanolic extract of cucumber peel could potentially be an anticholesterol with the percentage reduction of 28.50%; 35.45%; 39.59%; 45.82%; 51.24%; and 55.12% at 5 variations of concentration. The EC50 value was achieved at a concentration of 122.04 ppm.

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PENGARUH KOMBINASI EKSTRAK DAUN ASHITABA (Angelica keiskei Ito.) DAN DAUN SUKUN (Artocarpus communis) TERHADAP KADAR GLUKOSA DAN KOLESTEROL SECARA IN VITRO MENGGUNAKAN METODE FOTOMETRI

Cited by 2 publications

References 0 publications

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

LITERATURE REVIEW: CHEMICAL CONTENT AND PHARMACOLOGICAL ACTIVITY OF KERSEN LEAF (Muntingia calabura L.)

The Potency of Cucumber (Cucumis Sativus L.) Peel Extract as Anticholesterol

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