Penetrating keratoplasty for keratoconus: A long-term review of results and complications

Olson, Randall J.; Pingree, Michael; Ridges, Ryan; Lundergan, Maureen L; Alldredge, Claren; Clinch, Thomas E.

doi:10.1016/s0886-3350(00)00430-2

Cited by 135 publications

(82 citation statements)

References 10 publications

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“…These visual outcomes are comparable to results obtained in other studies using the big-bubble technique but involving the removal of the donor endothelium (15,16,23) . The incidence of graft rejection following DALK has been reported to range from 0% to 9.6% in various series (13,24,25) . This is significan- tly lower than the reported rates of 4%-31% following PK in patients with keratoconus (25,26) .…”

Section: Discussionmentioning

confidence: 99%

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Visual outcomes after deep anterior lamellar keratoplasty using donor corneas without removal of Descemet membrane and endothelium

Prazeres¹,

Müller²,

Rayes³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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Approved by the following research ethics committee: Hospital Oftalmológico de Sorocaba (# 1.326.225). RESUMO ABSTRACTPurpose: The optical quality of the interface after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique has been shown to be excellent, leading to results comparable to penetrating keratoplasty. However, there is little in the literature with respect to the controversy surrounding the preparation of the donor cornea. The purpose of this study was to evaluate visual acuity (VA) in patients with keratoconus who underwent DALK without removal of the donor graft endothelium. Methods: The records of 90 patients who underwent DALK without the removal of the Descemet membrane (DM) and endothelium were retrospectively reviewed. Data collected included uncorrected VA (UCVA) and spectacle-corrected VA (SCVA) at 7, 30, 180 days, and 1 year postoperatively. Contact lens-corrected visual acuity (CLVA) was evaluated after 1 year of the procedure. Results: UCVA was significantly better than preoperative values at 7 days (p<0.001), 30 days (p<0.001), 180 days (p<0.001), and 1 year (p<0.001) after surgery. The 1-year postoperative mean SCVA and CLVA also improved when compared with preoperative SCVA (p<0.001 for both). Conclusions: DALK utilizing donor corneas with attached Descemet membrane and endothelium results in satisfactory VA in patients with keratoconus.

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Section: Discussionmentioning

confidence: 99%

“…The incidence of graft rejection following DALK has been reported to range from 0% to 9.6% in various series (13,24,25) . This is significan- tly lower than the reported rates of 4%-31% following PK in patients with keratoconus (25,26) . We found no instances of graft rejection at 48 months of follow-up in our patients.…”

Section: Discussionmentioning

confidence: 99%

Visual outcomes after deep anterior lamellar keratoplasty using donor corneas without removal of Descemet membrane and endothelium

Prazeres¹,

Müller²,

Rayes³

et al. 2016

Arquivos Brasileiros De Oftalmologia

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“…A perda de células endoteliais que ocorre durante a cirurgia e a perda contínua destas durante os anos que se seguem deve ser considerada (15) .…”

Section: Discussionunclassified

Análise de nova técnica para o implante do anel de Ferrara no ceratocone

Oliveira

Moreira

Wahab

et al. 2004

Arq. Bras. Oftalmol.

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“…Based on disease severity, many treatment modalities exist including glasses and contact lenses for mild to moderate disease [2][3][4] while corneal graft preserved for more advanced disease [5]. High costs, need to long follow-ups, long periods for visual rehabilitation, risks of graft rejection or infection, wound dehiscence and suture-related problems make corneal grafts preserved for the last therapeutic choice by many ophthalmologists [6].…”

Section: Introductionmentioning

confidence: 99%

Aberrometric Outcomes of Intrastromal Corneal Ring Segment (KeraRing 355) Implantation Using PocketMaker Microkeratome in Patients with Keratoconus

Jadidi¹,

Nejat²,

Alishiri³

et al. 2017

J Clin Exp Ophthalmol

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Objective: To evaluate aberrometric changes in corneas with keratoconus implanted with intrastromal corneal ring segment (Keraring 355) during a 3-months follow-up. Design: Prospective, consecutive case seriesMethods: In this interventional study, 22 eyes of 21 keratoconic patients with mean age of 29 ± 6 years who underwent KeraRing 355 intrastromal corneal ring insertion using a Pocket Maker Microkeratome for channel creation and completed at least three months of follow-up were included. Uncorrected visual acuity (UCVA), best spectacle corrected visual acuity (BSCVA), refractive outcome, Orbscan finding and corneal aberrations were assessed.Results: Three months postoperately, Low order aberration (defocus and astigmatism) decreased significantly (P<0.001). No statistically significant changes were detected in total RMS, trefoil, secondary trefoil and coma. Moreover, a statistically significant increase in quatrefoil, secondary coma, spherical aberration and secondary spherical was found. In term of visual outcomes, the mean UCVA (in LogMAR value) improved significantly from 0.75 ± 0.33 to 0.31 ± 0.23 and the mean BSCVA improved (from 0.31 ± 0.16 to 0.19 ± 0.15) (P<0.05). The mean spherical refractive error improved (from -1.37 ± 1.36 to 0.01 ± 2.47) and the mean cylindrical refractive error decreased significantly (from -3.8 ± 1.03 to -2.1 ± 1.27 (P<0.001)). Also, the mean keratometry value decreased from 47.61 ± 2.03 to 42.50 ± 2.76. Conclusion: KeraRing 355 implantation provided significant improvement in low order aberrations but was not effective in high order aberrations (HOA) in low/moderate keratoconus patients. However, UCVA, BCVA, spherical and cylindrical refractive error and keratometry results improved significantly.

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Penetrating keratoplasty for keratoconus: A long-term review of results and complications

Cited by 135 publications

References 10 publications

Visual outcomes after deep anterior lamellar keratoplasty using donor corneas without removal of Descemet membrane and endothelium

Visual outcomes after deep anterior lamellar keratoplasty using donor corneas without removal of Descemet membrane and endothelium

Análise de nova técnica para o implante do anel de Ferrara no ceratocone

Aberrometric Outcomes of Intrastromal Corneal Ring Segment (KeraRing 355) Implantation Using PocketMaker Microkeratome in Patients with Keratoconus

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