Pencil-core Granuloma Forming 62 Years After Initial Injury

Zelickson, Blake R.; Goldberg, Leonard Harry; Wu, Wesley; Rubenzik, Marc; Motaparthi, Kiran

doi:10.12788/cutis.0459

Cited by 2 publications

(2 citation statements)

References 8 publications

(25 reference statements)

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“…As for the lesion to appear a lengthy process of disintegration of the "lead" before release of graphite is necessary [1], it is reasonable that a trauma that happened many years ago could not remember by our patient. The longest interval between implantation of a pencil core and diagnosis of the lesion was 62 years, in the forehead skin of a 71-year-old female [21]. Occasional cutaneous [1] and ocular [3] graphite foreign body granulomas may manifest as tumor-like lesions simulating malignant melanoma, as in the present case.…”

Section: Discussionmentioning

confidence: 51%

A graphite foreign body granuloma that caused palatal perforation. Case report and literature review

Tosiou,

Kalogirou,

Tosios

et al. 2024

Preprint

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Introduction: We present an unusual case of a graphite foreign body granuloma causing palatal perforation. Case description: A 62-year-old female presented with a macule on the hard palate clinically consistent with a blue nevus. On biopsy a black nodular mass was excised, establishing oroantral communication that was verified by a computed tomography scan. A diagnosis of malignant melanoma was strongly suspected, but microscopic examination showed a graphite foreign body granuloma. It was suggested that the graphite was implanted in a thin area of the palatal bone causing perforation. Conclusion: Graphite tattoos should be excised, both for diagnostics purposes and the possibility of causing tissue destruction by generating a foreign body granuloma reaction.

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Section: Discussionmentioning

confidence: 51%

A graphite foreign body granuloma that caused palatal perforation. Case report and literature review

Tosiou,

Kalogirou,

Tosios

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

A graphite foreign body granuloma causing palatal perforation. Case report and literature review

Tosiou

Kalogirou

Vlachodimitropoulos

et al. 2023

Preprint

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Purpose To present an unusual case of a graphite foreign body granuloma causing palatal perforation and review the literature on graphite deposition in the oral mucosa. Methods A 62-year-old female patient presented with a macule on the hard palate clinically consistent with a blue nevus. During excisional biopsy a black nodular mass was found beneath the macule that extended through a tunnel-like palatal deficit towards the nasal cavity. Oroantral communication was verified by a computed tomography scan indicating a diagnosis of malignant melanoma. Results Microscopic examination showed a graphite foreign body granuloma. It was suggested that the core was implanted in a thin area of the palatal bone and the foreign body granuloma caused the tunnel-like resorption. Conclusion Graphite tattoo may be included in the differential diagnosis of solitary pigmented lesions of the oral mucosa and should be excised, as it may cause tissue destruction though the development of a foreign body granuloma reaction.

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Pencil-core Granuloma Forming 62 Years After Initial Injury

Abstract: Pencil-core granulomas can arise even decades after the lead is embedded in the skin.• It is important to biopsy to confirm the diagnosis, as pencil-core granulomas can very closely mimic melanomas.

Cited by 2 publications

References 8 publications

A graphite foreign body granuloma that caused palatal perforation. Case report and literature review

A graphite foreign body granuloma that caused palatal perforation. Case report and literature review

A graphite foreign body granuloma causing palatal perforation. Case report and literature review

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