Pencil beam all-optical ultrasound imaging

Alles, Erwin J.; Noimark, Sacha; Zhang, Edward; Beard, Paul C.; Desjardins, Adrien E.

doi:10.1364/boe.7.003696

Cited by 56 publications

(35 citation statements)

References 28 publications

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“…Although photoacoustic transmitters were integrated with optical fibers, it is not easy to implement a focusing scheme due to fabrication challenges. There are only a few work reported for imaging and therapy . In addition, although there exists various efficient photoacoustic composites recently developed, one may need to further improve the conversion efficiencies of existing photoacoustic materials or find alternative photoacoustic materials with a higher conversion efficiency.…”

Section: Discussionmentioning

confidence: 99%

Efficient Photoacoustic Conversion in Optical Nanomaterials and Composites

Lee

Baac

et al. 2018

Advanced Optical Materials

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approaches. While addressing the limitations of the electrical counterparts (e.g., massive amounts of radio frequency (RF) cabling and electromagnetic (EM) interference), a photoacoustic approach for gene rat ing high-amplitude ultrasound has created new opportunities.Active research on efficient photo acoustic materials has started with the development of photoacoustic contrast mediums (e.g., exogenous contrast particles) for contrast enhancement. [3][4][5] Recent advances in nanofabrication technologies have allowed to develop more efficient photoacoustic contrast mediums, [3] such as metal nanoparticles having enhanced optical absorption due to optical resonance. Later, by coating such nanoparticles on a flat substrate, layered structures were developed for generating high-amplitude ultrasound. Among many nanoparticles, gold nanoparticles were widely used owing to strong resonance. [6] In fact, these initial efforts to increase photoacoustic conversion were focused on increasing light absorption, while the critical role of thermal expansion for photoacoustic generation were often overlooked.To enhance thermal expansion for photoacoustic generation, researchers have started to fabricate composite materials, composed of light-absorbing materials mixed with polymers with high thermal expansion coefficients. These polymer-based composites significantly enhance photoacoustic conversion efficiency. Among many polymers, polydimethylsiloxane (PDMS) is exclusively used because of its high thermal expansion, optical transparency, and acoustic impedance comparable to that of water. [7][8][9][10][11] Photoacoustic pulses generated with PDMSbased composites have the characteristics of high amplitude and high frequency, which have enabled interesting applications such as cavitation-based therapy [12] and imaging. [13] For photoacoustic composites, there are a myriad of light-absorbing nanomaterials such as metal absorbers [6] and carbon nanomaterials (e.g., carbon black (CB), [14] carbon nanotube (CNT), [7,10] carbon nanofiber (CNF), [9] candle soot (CS), [8] and reduced graphene oxide (rGO) [15] ). These light-absorbing materials of nanometer sizes have an advantage over microscale absorbing materials [7] in facilitating heat transfer from the light absorbers into the surrounding mediums. Such facilitated heat transfer is another key factor that contributes to photoacoustic energy conversion.In this Review, we will start with general considerations of photoacoustic generation in nanomaterial composites. Various photoacoustic composites enabling interesting applications will be introduced. In addition, recent efforts will be reviewed from an application perspective. Also, we will discuss outlook and future directions.Photoacoustic pulses generated by pulsed laser irradiation have the characteristics of high frequency and wide bandwidth, which are desirable for imaging and sensing. Efficient photoacoustic composites have been developed for fabricating photoacoustic transmitters capable of generating highamplitude ultrasound....

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Section: Discussionmentioning

confidence: 99%

Efficient Photoacoustic Conversion in Optical Nanomaterials and Composites

Lee

Baac

et al. 2018

Advanced Optical Materials

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“…Thus, the lateral resolution of the system was dependent on the imaging depth and decreased with depth; at its widest the lateral resolution was approximately 2.0 mm. The use of a larger diameter ultrasound transmitter, or one with a concave surface, would lead to improved directivity, and thus improved lateral resolutions [23].…”

Section: Discussionmentioning

confidence: 99%

Robotic Control of a Multi-Modal Rigid Endoscope Combining Optical Imaging with All-Optical Ultrasound

Dwyer¹,

Colchester

Alles

et al. 2019

2019 International Conference on Robotics and Automation (ICRA)

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Fetoscopy is a technically challenging surgery, due to the dynamic environment and low diameter endoscopes often resulting in a limited field of view. In this paper, we report on the design and operation of a robotic multimodal endoscope with optical ultrasound and white light stereo camera. The manufacture and control of the endoscope is presented, along with large area (80 mm × 80 mm) surface visualisations of a placenta phantom using the optical ultrasound sensor. The repeatability of the surface visualisations was found to be 0.446 ± 0.139 mm and 0.267 ± 0.017 mm for a raster and spiral scan, respectively.

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“…There have been no optical technologies directly utilized in the diagnosis or treatment of ICAS. Alles et al 46 were the first to image ex vivo aortic tissue with an optically transmitted acoustic beam. They demonstrated side-branch blood vessels with great accuracy (Fig.…”

Section: Current Optical Applicationsmentioning

confidence: 99%

Perspective review on applications of optics in cerebral endovascular neurosurgery

2019

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Cerebral endovascular neurosurgery has transformed the way we manage cerebrovascular disease. Several landmark trials have demonstrated the effectiveness of endovascular techniques leading to continued technological development and applications for various diseases. The utilization of optical technologies and devices is already underway in the field of endovascular neurosurgery. We discuss the contemporary paradigms, challenges, and current optical applications for the most common cerebrovascular diseases: carotid atherosclerotic disease, cerebral aneurysms, intracranial atherosclerosis, and dural arteriovenous fistulas. We also describe needs-based opportunities for future optical applications, with the goal of providing researchers a sense of where we feel optical technologies could impact the way we manage cerebral disease.

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Pencil beam all-optical ultrasound imaging

Cited by 56 publications

References 28 publications

Efficient Photoacoustic Conversion in Optical Nanomaterials and Composites

Efficient Photoacoustic Conversion in Optical Nanomaterials and Composites

Robotic Control of a Multi-Modal Rigid Endoscope Combining Optical Imaging with All-Optical Ultrasound

Perspective review on applications of optics in cerebral endovascular neurosurgery

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