Pen devices for self-injection: contrasting measured injection force with users’ perceived ease of injection

Schneider, Andréas; Lange, Jakob

doi:10.1080/17425247.2018.1415884

Cited by 7 publications

(8 citation statements)

References 57 publications

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“…A total of three user interface design versions of the connected self-injection system were thus evaluated. The usability of each version was investigated in an independent and separate study of formative testing using eye-tracking as a research method (ETS1-3) based on single site visits [34,60,61]. The insights obtained in eye-tracking studies ETS1 and ETS2 guided the subsequent Design Iterations A and B, respectively.…”

Section: Methodsmentioning

confidence: 99%

“…Formative usability studies have proven indispensable tools to advance device development [32,33]. Traditionally, new product development has advanced in cycles of optimizing the user interface of pen systems and (re-) assessing patient preferences [34]. Specifically, users' self-reported ratings or responses to openended questions [18,21,35,36], interviews [37,38], or observations [39][40][41] have been established as standard methods to assess patient engagement with mechanical autoinjectors or dial-anddose insulin pens [33,[42][43][44].…”

Section: Introductionmentioning

confidence: 99%

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Toward a new age of patient centricity? The application of eye-tracking to the development of connected self-injection systems

Lohmeyer

Schneider

Jordi

et al. 2019

Expert Opinion on Drug Delivery

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Background: Increasing interest in digitally enhanced drug delivery tools urges both industry and academia to rethink current approaches to product usability testing. This article introduces mobile eyetracking, generating detailed contextual data about user engagement with connected self-injection systems as a new methodological approach to formative usability assessment. Methods: A longitudinal case study with a total of 35 injection-naïve participants was conducted. In three consecutive experiments, eye-tracking was applied to formative usability testing of a novel connected self-injection device. Three eye-tracking derived usability indicators were established to assess product effectiveness, efficiency, and ease of use. Results: Analysis of the data revealed events of user hesitation, process interruption and unintended action, and these occurrences could either be completely eliminated or significantly reduced throughout the process (product effectiveness). At the same time, the overall use duration decreased from 86.1 to 58.7 sec (product efficiency). Analysis revealed that product modifications successfully guided user attention to those interface elements most relevant during each task, thereby improving product easeof-use. Conclusions: The step-wise improvement in the usability indicators demonstrates that iteratively applying eye-tracking methods effectively supports the user-centered design of connected selfinjection systems. The results highlight how eye-tracking can be employed to gain an in-depth understanding of patient engagement with novel healthcare technologies. ARTICLE HISTORY

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Toward a new age of patient centricity? The application of eye-tracking to the development of connected self-injection systems

Lohmeyer

Schneider

Jordi

et al. 2019

Expert Opinion on Drug Delivery

Self Cite

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“…However, the feasibility of longer injection times using handheld drug delivery devices in terms of usability has been mostly neglected. This scarcity of studies is unexpected, because the ability of patients to safely and effectively perform self-injections is emphasized as a prerequisite for successful product validation, regulatory approval, and commercial uptake [26,40].…”

Section: Introductionmentioning

confidence: 99%

Hold the device against the skin: the impact of injection duration on user’s force for handheld autoinjectors

Schneider

Mueller

Jordi

et al. 2019

Expert Opinion on Drug Delivery

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Background: The recent development of high-volume subcutaneous drug delivery using handheld autoinjectors has resulted in longer injection durations. However, the usability of long injections has been neglected. This study aimed to investigate the effects of injection duration on users' ability to apply injections while holding the device against the skin at the injection site. Methods: Thirty-two participants among patients, caregivers, and health-care professionals simulated three injections with different injection durations to evaluate usability and user's force. Linear and quantile regression were then applied to determine the impact of the injection duration on response variables related to user's force. Results: A significant negative effect of injection time was found on both the minimum and mean user's force applied. Initial empirical evidence was also determined on the negative association being more pronounced for users exerting lower force to hold the device against the skin. Conclusions:The results that are subject to future clinical validation suggest the feasibility of injections lasting up to approximately 30 s using handheld autoinjectors. The participants of the simulated use study successfully applied long-duration injections regardless of disease states, age, or visual and dexterity impairments. ARTICLE HISTORY

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“…21 Because assumptions about which features would be important to end-users may not always be accurate, it is critical to holistically integrate their feedback to fully understand preferences for medical devices. 22 This study sought to qualitatively understand perceptions about glucagon delivery devices and potential effects of different delivery devices for severe hypoglycemia, specifically nasal glucagon and autoinjector glucagon, from the perspective of the patient, caregiver, and acquaintance.…”

mentioning

confidence: 99%

Perceptions About Glucagon Delivery Devices for Severe Hypoglycemia: Qualitative Research With Patients, Caregivers, and Acquaintances

Bajpai

Cambron-Mellott

Peck

et al. 2019

Clinical Therapeutics

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Purpose: People with diabetes taking insulin are at risk of severe hypoglycemia, an unpredictable, lifethreatening event that requires assistance from others. Outside the clinical setting, glucagon is indicated for the treatment of hypoglycemia. However, there is significant unmet medical need to improve successful administration of glucagon by caregivers and acquaintances. This study assesses perceptions about glucagon delivery and potential effects of 2 glucagon delivery devices for severe hypoglycemia.

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Pen devices for self-injection: contrasting measured injection force with users’ perceived ease of injection

Cited by 7 publications

References 57 publications

Toward a new age of patient centricity? The application of eye-tracking to the development of connected self-injection systems

Toward a new age of patient centricity? The application of eye-tracking to the development of connected self-injection systems

Hold the device against the skin: the impact of injection duration on user’s force for handheld autoinjectors

Perceptions About Glucagon Delivery Devices for Severe Hypoglycemia: Qualitative Research With Patients, Caregivers, and Acquaintances

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