Pelvic Solitary Plasmacytoma: Computed Tomography and Magnetic Resonance Imaging Findings with Histopathologic Correlation

Wang, Ying; Zhu, Xiu‐Liang; Peeroo, Mohamad Wasil; Qian, Zi-Hua; Shi, Dan; Wei, Shumei; Yu, Ri‐Sheng

doi:10.3348/kjr.2015.16.1.146

Cited by 12 publications

(6 citation statements)

References 19 publications

(24 reference statements)

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“…A recent retrospective series of 10 patients with histological confirmation of SBP of the pelvis, analyzed the correlation between CT, MRI and histopathologic features. 10 Although few patients were analyzed (with 50% cases affecting the ilium), this study found a correlation between imaging characteristics and histopathologic grade, with superiority of CT on characterizing the type of bone destruction and concordance with histology findings, and MRI with better value as a prognostic method for reexamination after radiotherapy.…”

Section: Discussionmentioning

confidence: 65%

“…8 Regarding SBP, males are twice likely to be more affected than females (65% vs. 35%) and the median age of presentation is a decade younger than that of patients with MM (55 vs. 65 years). 1,9,10 People older than 60 years old are more affected (up to 9 times more), 8 although there is also evidence that younger people can be affected if preceding trauma. 2 One observational study also tried to make conclusions about the influence of race and plasmacytomas, and found that Whites had intermediate risk comparing to Black (higher risk) and Asians, although this finding was not statistically significant and more studies would be necessary to make considerations about this relationship.…”

Section: Discussionmentioning

confidence: 99%

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Solitary Bone Plasmacytoma of the Pelvis: A Rare Tumor

et al. 2016

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Solitary bone plasmacytomas are part of a wide range of monoclonal neoplasms that share a common progenitor in the B lymphocyte lineage. In their particular case, a single bone lesion is found, most frequently on the axial skeleton, having evidence of no other osteolytic lesions or systemic involvement. Diagnosis can sometimes prove to be difficult as they are rare tumors, occurring in 3 to 5% (up to 10% in some series) of patients with plasma cell neoplasms, with important considerations regarding the differential diagnosis. We report a case of a solitary bone plasmacytoma, found on the ala of the left ilium of a patient during a routine consult due to hip pain.

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Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Solitary Bone Plasmacytoma of the Pelvis: A Rare Tumor

et al. 2016

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“…SBP is classified into three grades according to the differentiation degree of tumor cells. 10 Grade I tumor cells resemble normal plasmacytes without obvious atypia. Grade II tumor cells have obvious atypia and nuclear division can be seen.…”

Section: Discussionmentioning

confidence: 99%

“…It can also involve pelvis, humerus, femur and skull. 10,11 It is rare to occur in the maxillofacial bones. The clinical symptoms of SBP are lack of specificity.…”

Section: Discussionmentioning

confidence: 99%

Solitary plasmacytoma of maxillofacial bones: correlation of CT features with pathological findings

Liu

2020

Dentomaxillofacial Radiology

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Objective: To explore the CT features of solitary plasmacytoma (SP) of maxillofacial bones and correlation with pathological findings. Methods and materials: We retrospectively reviewed the clinical, CT and pathological features of SP in the maxillofacial bones. 16 patients with clinically and histologically proven SP of maxillofacial bones were involved. They were aged from 27 to 79 years old (median 55.5 years old), and included 12 males and 4 females (males vs females: 3:1). All patients performed CT examination, in whom 13 patients underwent enhanced scanning and 3 plain scanning. The CT images were assessed for lesion location, size (maximum diameter), shape (round, oval and irregular), boundary (defined and illdefined), bone changes (bone destruction, residual bone, sclerotic margin and periosteal reaction), density of soft tissue mass and enhancement manifestations, and invasion of adjacent structures. Results: 13 patients suffered from SP in the mandible, 2 in the zygoma, and 1 in the maxilla and hard palate. The maximum diameter of lesions ranged from 2.4 to 8.2 cm (mean 3.93 ± 1.435 cm). Most lesions were founded as a solitary osteolytic lesions (15/16, 93.75%) with round or ovoid shape (13/16, 81.25%), smooth margin (16/16, 100%) and defined boundary (16/16, 100%) in bone marrow. They destroyed bone cortex (15/16, 93.75%) and had residual bone (10/16, 62.5%), without sclerosis margin (15/16, 93.75%) and periosteal reaction (14/16, 87.5%). They easily formed soft tissue masses (16/16, 100%) and invade adjacent anatomical structures (15/16, 93.75%). The density of lesions was usually uniform (12/16, 75%) with strong enhancement. There was a significant difference in CT values between plain and enhanced scanning [50.75 ± 9.140 Hounfield unit (HU) vs 101.0 ± 28.830 HU; p < 0.001), with the mean difference of CT values 50.25 HU. Conclusions: SP is predominant in the mandible of elderly male patients. A solitary, round or ovoid, well-defined, osteolytic, invasive mass in bone marrow, which destroys bone cortex, has residual bone, no sclerosis margin and periosteal reaction, and shows strong enhancement, is suggestive of this diagnosis.

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“…Histological grade often dictates management and a moderate-dose radiotherapy combined with surgery is occasionally suggested for optimal treatment with sufficient local control. Patients with a high-grade histology may benefit from adjuvant chemotherapy [37]. Histological grade often dictates management and a moderate-dose radiotherapy combined with surgery is occasionally suggested for optimal treatment with sufficient local control.…”

Section: Plasmacytomamentioning

confidence: 99%

Primary Osseous Malignancies of the Spine

et al. 2023

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Malignant primary vertebral tumours comprise an uncommon group of primary bone malignancies that can pose a diagnostic and therapeutic challenge. The most frequently encountered malignant primary vertebral tumours include chordoma, chondrosarcoma, Ewing sarcoma and osteosarcoma. These tumours often present with nonspecific symptoms, such as back pain, neurologic deficits and spinal instability, which can be confused for the more commonly encountered mechanical back pain and may delay their diagnosis and treatment. Imaging, including radiography, computed tomography (CT) and magnetic resonance imaging (MRI) is crucial for diagnosis, staging, treatment planning and follow-up. Surgical resection remains the mainstay of treatment for malignant primary vertebral tumours, but adjuvant radiotherapy and chemotherapy may be necessary for achieving complete tumour control depending on the type of tumour. In recent years, advances in imaging techniques and surgical approaches, such as en-bloc resection and spinal reconstruction, have improved the outcomes for patients with malignant primary vertebral tumours. However, the management can be complex due to the anatomy involved and the high morbidity and mortality associated with surgery. The different types of malignant primary vertebral lesions will be discussed in this article with an emphasis on the imaging features.

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Pelvic Solitary Plasmacytoma: Computed Tomography and Magnetic Resonance Imaging Findings with Histopathologic Correlation

Cited by 12 publications

References 19 publications

Solitary Bone Plasmacytoma of the Pelvis: A Rare Tumor

Solitary Bone Plasmacytoma of the Pelvis: A Rare Tumor

Solitary plasmacytoma of maxillofacial bones: correlation of CT features with pathological findings

Primary Osseous Malignancies of the Spine

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