Pelvic mass – diagnosis and management

Majmudar, T.; Abdel-Rahman, H.

doi:10.1016/j.ogrm.2008.05.004

Cited by 3 publications

(2 citation statements)

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“…Pelvic masses are a common cause for admission of patients to gynecology clinics, and one of the most common reasons for referral to gynecologic oncology departments to assess the possibility of uterine or ovarian malignancies. A pelvic mass may present as an impalpable asymptomatic incidental finding or even a large mass extended from pelvis to abdominal cavity ( 1 ). The most prevalent type of pelvic masses is ovarian masses, which include cysts and tumors.…”

Section: Introductionmentioning

confidence: 99%

“…Goldstein described the approach, as well as available methods and techniques, for diagnosis of postmenopausal cystic adnexal masses ( 6 ). In 2009, Yamamoto et al suggested a new index as RMI 4, which adds consideration of tumor size as: “RMI ( 1 , 2 , 3 ) = ultrasound findings × CA125 × menopausal status “( 7 ). For RMI 1, possible abnormal ultrasound findings (U) include multilocular cystic lesion, solid lesion, bilateralism, ascites, and metastasis.…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic Value of the Risk of Malignancy Index (RMI) for Detection of Pelvic Malignancies Compared with Pathology

Karimi-Zarchi¹,

Mojaver²,

Rouhi³

et al. 2015

Electron physician

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IntroductionPelvic masses are among most the common causes of patient admission into gynecology clinics and one of the most common reasons for referral to gynecologic oncology departments due to the risk of uterine or ovarian malignancies. The aim of this study is to compare the four indices of the risk of malignancy index (RMI 1–4), as a combination of menstrual status, radiological findings, and serum CA125 concentration, for discrimination of benign from malignant pelvic masses.MethodsThis retrospective descriptive and analytic study was conducted on 200 patients with pelvic mass, post-surgery, and who were referred to the oncology department in Shahid Sadoughi hospital of Yazd (Iran) between June 2007 and September 2011. Data regarding demographics, pathology reports, paraclinical and clinical tests were analyzed. The four RMI indices were separately used for determination of benign vs. malignant masses using the optimized cutoff points, ROC curve, sensitivity, specificity, predictive value of positive and negative, and accuracy. Finally, p value for each index was calculated, and a final discrimination power was measured by using SPSS version 17 software.ResultsThe calculated p values in the four RMI indices in ultrasound findings indicated statistical significance, and the RMI 2 showed the highest level of accuracy or diagnostic performance. RMI 2 had a cutoff point of 90, an under-chart area 86.7, 79.36% sensitivity, 78.95% specificity, 58.44%, positive predictive value, 90.08% negative predictive value, and 78.93% accuracy, and a p value of 0.004. However, this relationship was found not to be meaningful using CT scan images.ConclusionsUsing RMI 2 for differentiation of malignant from benign pelvic masses is a reliable method with ultrasound findings.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diagnostic Value of the Risk of Malignancy Index (RMI) for Detection of Pelvic Malignancies Compared with Pathology

Karimi-Zarchi¹,

Mojaver²,

Rouhi³

et al. 2015

Electron physician

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Evaluation of female pelvic mass by MRI and CT scan

Alhashlan¹,

Alqufayli²,

Almonajem³

et al. 2022

JCPCR

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The female pelvis contains several organs. A thorough understanding of the anatomy of the pelvic region is crucial for the diagnosis of any disease that could attack the female pelvis-and in order to determine treatment. For this reason, therefore, here is a gross anatomy of the pelvis, with a particular focus on the ovaries. The organs under focus are the reproductive system organs, which are: two fallopian tubes, two ovaries, uterus, endometrium, myometrium, cervix and vagina. Of particular interest is the middle compartment, which is found only in the female pelvis, while the anterior and posterior compartments are located in both genders. The middle compartment contains the female genital organs, which are: the ovaries, uterine tubes, uterus and vagina. This article will have a specific focus on the ovaries.

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Clinical Significance of Thrombocytosis and CA125 as Predictor of Malignancy in Gynecological Pelvic Mass

Salamit¹

2018

Int.J.Curr.Res.Aca.Rev.

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Article InfoWe attempted to determine the increasing of platelet counts (> 450.000 /microliter) and Cancer Antigen 125 (CA125) serum level (> 35 U/mL) as useful tools for predicting and confirming malignancy in gynaecological pelvic mass. A prospective unmatched hospital based case-control study carried out about One hundred & ten women were enrolled in our study, divided into two group 60 women were control group (free of gynaecological pelvic mass) which were considered as -eligible entrants‖ into the study. Other group include 50 women above 15 years old with gynaecological pelvic mass were all candidate for laparotomy and using different diagnostic methods like clinical examination, imaging techniques (U/S, CT scan and MRI) and laboratory test (platelet count, CA125 and Histopathology). The data of those were subjected to statistical analysis (sensitivity, specificity, accuracy, NPV and PPV) which calculated to considered if it is statistically significant or not. Serum CA125 and blood platelets count were tested for validity when used as a test to predict a diagnosis of malignancy in gynaecological pelvic mass differentiating it from benign gynaecological pelvic mass. Both tests showed a very high validity in diagnosis (ROC area >0.95), with serum CA125 showing a marginally higher validity (ROC area larger by 0.017 only). Both ROC areas were significantly higher than the 0.5 area associated with an equivocal test. Platelets counts had a perfect cut-off value of ≥385.000 All study subjects with a blood platelets count equal or greater than 385.000 were malignant, while everybody below this cut-off value was healthy. For serum CA125 testing negative at the highest sensitivity (100% sensitive) cut-off value of (≥27.1( would excluded a possible diagnosis of malignancy in favor of being healthy with 100% confidence. The optimum cut-off value is ≥41.7, which is also the 100% specific and thus 100% diagnostic cut-off value. Both blood platelet count (≥ 385 X 10 3 microlitter) & serum level of CA125 (≥ 41.7 U/mL) are useful predictor tools to confirm malignancy in gynecological pelvic mass.

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Pelvic mass – diagnosis and management

Cited by 3 publications

References 0 publications

Diagnostic Value of the Risk of Malignancy Index (RMI) for Detection of Pelvic Malignancies Compared with Pathology

Diagnostic Value of the Risk of Malignancy Index (RMI) for Detection of Pelvic Malignancies Compared with Pathology

Evaluation of female pelvic mass by MRI and CT scan

Clinical Significance of Thrombocytosis and CA125 as Predictor of Malignancy in Gynecological Pelvic Mass

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