Pellucid marginal corneal degeneration*1

Sridhar, Magadi Gopalakrishna; Mahesh, Sankaranarayana P.; Bansal, Akash; Nutheti, Rishita; Rao, Gullapalli N

doi:10.1016/j.ophtha.2003.09.035

Cited by 149 publications

(128 citation statements)

References 21 publications

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“…This altered corneal shape leads to against-the-rule astigmatism and visual acuity deterioration. [1][2][3][4][5][6] The etiology is unknown. 7 Different treatment modalities are utilized to manage the patients with PMD based on the severity of their disease, including spectacle, rigid gas permeable contact lens, intrastromal corneal ring segments (Intacs, KeraRing), and several other surgical techniques.…”

Section: Introductionmentioning

confidence: 99%

Outcome of complete intrastromal ring implantation using femtosecond laser in pellucid marginal degeneration

Jabbarvand

Hashemian

Khodaparast

et al. 2015

Eye

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Purpose To evaluate the effect of complete intrastromal corneal ring implantations on patients with pellucid marginal degeneration (PMD). Design Prospective interventional case series Patients and Methods Thirty-three eyes with PMD were included into the study. After pocket creation with femtosecond laser (Femtec; 20/10 PerfectVision), MyoRing implantation was performed. Uncorrected and corrected distance visual acuity (UDVA, CDVA), subjective refraction, keratometry, central corneal thickness, corneal biomechanical profile (Ocular Response Analysis), and whole-eye wavefront aberrometry (iTrace) were evaluated preoperatively and also postoperatively, 1 month, 3 months, 6 months, and 1 year after the operation. Results One month after surgery, significant improvements were observed in UDVA (ANOVA; P = 0.02), mean keratometry, sphere (ANOVA; P o0.001), and cylinder (ANOVA; P = 0.04) with no significant changes afterwards. No significant change occurred in the corneal biomechanical profile. Primary coma and trefoil reduced after 1 year (ANOVA; P values were 0.02 and 0.06, respectively). Primary spherical aberration significantly increased according to the 1-year follow-up (ANOVA; Po0.001). No significant complication was observed. Conclusion MyoRing is considered as a treatment modality for spherocylindrical correction in patients with PMD, with an acceptable safety and efficacy profile.

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Section: Introductionmentioning

confidence: 99%

Outcome of complete intrastromal ring implantation using femtosecond laser in pellucid marginal degeneration

Jabbarvand

Hashemian

Khodaparast

et al. 2015

Eye

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“…3,8 The PMD can be diagnosed classically by slit-lamp examination, which shows a clear band of inferior corneal thinning extending from 4 to 8 o'clock. There is typically a 1 to 2 mm of uninvolved normal cornea.…”

Section: 2mentioning

confidence: 99%

“…3,8 In the early stages of PMD, soft toric lenses can be an option for improvement in visual acuity.…”

Section: Nonsurgical Corneal Rehabilitation Treatmentmentioning

confidence: 99%

Treatment of Pellucid Marginal Degeneration

Farrag¹,

Hussein²,

Ummar³

2017

International Journal of Keratoconus and Ectatic Corneal Diseases

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Purpose: To summarize the recent trends in the treatment of pellucid marginal degeneration (PMD) based on available published data.Method and literature search: A PubMed search was conducted with combinations not limited to the following search terms: Pellucid marginal degeneration, Corneal ectasia, Corneal collagen cross-linking (CXL), Intracorneal ring segments (ICRS), Contact lens, Keratoplasty in corneal ectasia. A review of the search results was performed and relevant articles to the topic were included. Summary:Ophthalmologists have got a wide array of therapeutic modalities for the management of PMD. However, the key to optimal treatment is careful clinical assessment of patients and their visual requirements and tailoring the treatment to individual patients.

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“…Pellucid Marginal Degeneration (PMD) is another ectatic pathology that is rarely detected. PMD is a bilateral, noninflammatory, progressive peripheral inferior corneal thinning disorder (1,2). Diagnosis is based on the presence of corneal thinning with ectasia characterized by a peripheral band of thinning of the inferior cornea with 1 to 2 mm of normal cornea between this area and the limbus (2,3).…”

Section: Introductionmentioning

confidence: 99%

“…The topographic appearance shows a classical "butterfly" pattern that demonstrates large amounts of against-the-rule astigmatism as measured by simulated keratometry and inferior thinning. PMD can also be diagnosed by performing a pachymetric map of the entire cornea, as well as by elevation corneal maps using placido-ring-based videokeratoscopy technology (1).…”

Section: Introductionmentioning

confidence: 99%