Peliosis of the Liver and Spleen

Abstract

Peliosis is a comparetively rare pathological entity characterized by the gross appearance of multiple cyst-like, blood-filled cavities within parenchymatous organs. Peliosis has been related to several underlying debilitating illnesses, such as tuberculosis, hematological malignancies, AIDS, and posttransplant immunodeficiency, as well as intravenous drug abuse, chronic alcoholism, and in conjunction with intake of oral contraceptives or the abuse of anabolic-androgenic steroids. The classical pathoanatomical concept is based on the opinion that peliosis exclusively develops in organs belonging to

Update of Key Mechanism of Hepatic Peliosis

“…Walker et al [11] the gross inspection of the peliotic lesions show the cut sections a "swiss cheese" appearance. Microscopically, there were two different types of peliosis can be identified in the liver: first type, parenchymal peliosis, composed of irregular cavities that outer lining was not be sinusoidal cells or fibrous tissue; and the second one, phlebectatic peliosis, was regular, spherical cavities protected by endothelium or fibrosis Tsokos et al [12]. The causes of peliosis hepatica is unknown and it occasionally observed in human liver Craiget et al [13] Many author interests to better understand explanation of liver peliosis as Munoz et al [14] explain Peliosis Hepatis to super expression of fas legend a Complication of the Ise of Oral Contraceptives in a Patient with Myelodysplasia.…”