Peliosis and gummatous syphilis of the liver: A case report

Chen, Junfa; Chen, Weixia; Zhang, Hongying; Zhang, Wenyan

doi:10.3748/wjg.14.1961

Cited by 16 publications

(4 citation statements)

References 4 publications

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“…The related drugs include anabolic steroids, diethylstilbestrol, corticosteroids, immunosuppressant, [3,4] tamoxifen, [5] androgen, [6] thiopurine, [7] and oral contraceptives. [8,9] In addition, a variety of infectious diseases, such as Bartonella henselae, [10] tuberculosis, [11] acquired immunodeficiency syndrome, [12] gummatous syphilis [13] are reported to be associated with PH. Moreover, PH has been recognized to be concomitant with HCC [14] and hematological malignancies [15] in some cases.…”

Section: Discussionmentioning

confidence: 99%

Peliosis hepatis

Dai

Ren²,

Song³

et al. 2017

Medicine

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Rationale:Peliosis hepatis (PH) is a rare tumor-like liver lesion composed of multiple blood-filled cavities within the liver parenchyma. It is hard to differentiate PH from other liver lesions by imaging, such as carcinoma, metastases, or abscess.Patient concerns:Here, we reported 2 cases that presented with liver lesions under ultrasound and computed tomography (CT) scanning, without any history of liver diseases or drug usage traced back.Diagnoses:Liver biopsy and laparoscopy were processed, and the lesions were eventually diagnosed as PH by histopathology, which microscopically presented with multiple sinusoidal dilatations with blood-filled cystic spaces.Interventions:After the liver biopsy or laparoscopy, the patients were discharged and followed up in the clinic.Outcomes:Both patients were followed up for at least 1 year with good recovery.Lessons:PH should always be recognized in the differentiation of liver lesions, particularly indistinctive lesion(s) without any history of liver-related diseases.

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Section: Discussionmentioning

confidence: 99%

Peliosis hepatis

Dai

Ren²,

Song³

et al. 2017

Medicine

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“…PH is often asymptomatic. Nevertheless, a variety of symptoms, including dyspepsia, abdominal pain, abdominal distension, fever and jaundice secondary to cholestasis, have been reported. Others might be found because of the complications, such as liver failure, portal hypertension and intraperitoneal bleeding due to hepatic rupture.…”

Section: Discussionmentioning

confidence: 99%

Peliosis hepatis: A mimicker of hepatic tumors

2013

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Peliosis hepatis (PH) is a rare benign liver lesion, characterized by the presence of multiple blood-filled cavities and marked dilation of the hepatic sinusoids throughout the hepatic parenchyma. It is often confirmed after the liver resection or liver biopsy. In the present study, we report a case of a 41-year-old woman who presented with a asymptomatic right hepatic mass. The imaging findings of the mass, including computed tomography and magnetic resonance imaging, showed centrifugal progression of enhancement during the portal and delayed phases. Because of the possibility of hepatic malignancy, partial resection of the liver was performed. The final pathological diagnosis was PH. By referring to the relevant literature, we conclude that, as a result of insignificant clinical manifestation and imaging features, PH should be kept in mind for patients with hepatic mass.

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“…Liver function tests are consistent with hepatitis [11]. Only one case of focal liver lesion associated with secondary syphilis has been reported until now [12], while focal liver lesions more frequently develop in tertiary syphilis [13][14][15][16][17]. In terms of diagnosis, liver biopsy is often non-specific with the definite evidence of T. Pallidum in only half of the cases [18].…”

Section: Prof D Conte Dr R E Rossimentioning

confidence: 91%