PEI-based functional materials: Fabrication techniques, properties, and biomedical applications

Fattahi, Nadia; Gorgannezhad, Lena; Masoule, Shabnam Farkhonde; Babanejad, Niloofar; Ramazani, Ali; Raoufi, Mohammad; Sharifikolouei, Elham; Foroumadi, Alireza; Khoobi, Mehdi

doi:10.1016/j.cis.2024.103119

Cited by 8 publications

(1 citation statement)

References 455 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cationic polymers have received an important role in various applications, such as drug and gene delivery systems, antimicrobial agents, surfactants for organo-modification of layered silicates, and many others [ 79 , 80 , 81 , 82 ]. Here, many synthetic and naturally-based cationic polymers, e.g., poly(ethylene imine), poly(amino acids), and chitosan, have been used for aforementioned applications [ 83 , 84 , 85 , 86 , 87 ]. From the family of poly(2-oxazolines), partially hydrolyzed poly(2-alkyl-2-oxazolines) have been used as cationic vectors for gene delivery [ 88 , 89 , 90 , 91 ].…”

Section: Poly(2-isopropenyl-2-oxazoline) In Biomedical Applicationsmentioning

confidence: 99%

Poly(2-isopropenyl-2-oxazoline) as a Versatile Functional Polymer for Biomedical Applications

Kronek,

Minarčíková,

Kroneková

et al. 2024

Polymers

View full text Add to dashboard Cite

Functional polymers play an important role in various biomedical applications. From many choices, poly(2-isopropenyl-2-oxazoline) (PIPOx) represents a promising reactive polymer with great potential in various biomedical applications. PIPOx, with pendant reactive 2-oxazoline groups, can be readily prepared in a controllable manner via several controlled/living polymerization methods, such as living anionic polymerization, atom transfer radical polymerization (ATRP), reversible addition–fragmentation transfer (RAFT) or rare earth metal-mediated group transfer polymerization. The reactivity of pendant 2-oxazoline allows selective reactions with thiol and carboxylic group-containing compounds without the presence of any catalyst. Moreover, PIPOx has been demonstrated to be a non-cytotoxic polymer with immunomodulative properties. Post-polymerization functionalization of PIPOx has been used for the preparation of thermosensitive or cationic polymers, drug conjugates, hydrogels, brush-like materials, and polymer coatings available for drug and gene delivery, tissue engineering, blood-like materials, antimicrobial materials, and many others. This mini-review covers new achievements in PIPOx synthesis, reactivity, and use in biomedical applications.

show abstract

Section: Poly(2-isopropenyl-2-oxazoline) In Biomedical Applicationsmentioning

confidence: 99%

Poly(2-isopropenyl-2-oxazoline) as a Versatile Functional Polymer for Biomedical Applications

Kronek,

Minarčíková,

Kroneková

et al. 2024

Polymers

View full text Add to dashboard Cite

show abstract

Radiosensitization of breast cancer cells with AgBiS₂ nanodots: Preparation and in vitro evaluations

Xue,

Pilehvar,

Afshari

et al. 2024

Applied Organom Chemis

View full text Add to dashboard Cite

Radiotherapy (RT), which is a therapeutic treatment modality that is commonly used for cancer, employs high‐energy irradiation to induce the generation of reactive oxygen species (ROS) and to cause DNA damages. Nevertheless, the therapeutic efficacy of RT is predominantly constrained due to inadequate DNA damage in malignancies and deleterious impacts on healthy tissues. In the current study, bovine serum albumin (BSA)–coated AgBiS2 nanodots, also known as AgBiS2@ BSA nanodots, were developed for enhanced breast cancer treatment. This was accomplished by the use of an extremely simple and eco‐friendly method. Both scanning transmission electron microscopy (STEM) and scanning electron microscopy (SEM) images revealed that prepared nanoradiosensitizers, AgBiS2@ BSA, were spherical in shape and uniformly distributed. AgBiS2@ BSA nanodots possessed excellent biocompatibility and exhibit excellent monodispersity as well. Furthermore, in vitro assays such as MTT, colony formation assay, and intracellular ROS generation assay revealed the significant cell inhibitory impact of the produced AgBiS2@ BSA nanodots under X‐ray irradiation under X‐ray irradiation. Remarkably, the combined administration of AgBiS2@ BSA nanodots along with X‐ray irradiation increased ROS level within cells by increasing the localized radiation dosage and improving the anti‐tumor effectiveness of RT.

show abstract

Lignin: A valuable and promising bio-based absorbent for dye removal applications

Fattahi,

Kashif

et al. 2024

International Journal of Biological Macromolecules

View full text Add to dashboard Cite

PEI-based functional materials: Fabrication techniques, properties, and biomedical applications

Cited by 8 publications

References 455 publications

Poly(2-isopropenyl-2-oxazoline) as a Versatile Functional Polymer for Biomedical Applications

Poly(2-isopropenyl-2-oxazoline) as a Versatile Functional Polymer for Biomedical Applications

Radiosensitization of breast cancer cells with AgBiS₂ nanodots: Preparation and in vitro evaluations

Lignin: A valuable and promising bio-based absorbent for dye removal applications

Contact Info

Product

Resources

About

PEI-based functional materials: Fabrication techniques, properties, and biomedical applications

Cited by 8 publications

References 455 publications

Poly(2-isopropenyl-2-oxazoline) as a Versatile Functional Polymer for Biomedical Applications

Poly(2-isopropenyl-2-oxazoline) as a Versatile Functional Polymer for Biomedical Applications

Radiosensitization of breast cancer cells with AgBiS2 nanodots: Preparation and in vitro evaluations

Lignin: A valuable and promising bio-based absorbent for dye removal applications

Contact Info

Product

Resources

About

Radiosensitization of breast cancer cells with AgBiS₂ nanodots: Preparation and in vitro evaluations