Pegylated Interferon‐α‐2a plus Ribavirin for Treatment‐Naive Asian Patients with Hepatitis C Virus Genotype 1 Infection: A Multicenter, Randomized Controlled Trial

Liu, Chen–Hua; Liu, Chun‐Jen; Lin, Chih–Lin; Liang, Cheng‐Chao; Hsu, Shih‐Jer; Yang, Sheng‐Shun; Hsu, Ching–Sheng; Tseng, Tai‐Chung; Wang, Chia-Chi; Lai, Ming‐Yang; Chen, Jun-Herng; Chen, Pei‐Jer; Chen, Ding‐Shinn; Kao, Jia‐Horng

doi:10.1086/592579

Cited by 177 publications

(243 citation statements)

References 37 publications

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“…Interestingly, it has also been well documented that East Asians have higher SVR rates than patients of European ancestry. 22,23 The SVR rates across different population groups displayed a striking concordance with C allele frequency which emphasizes the greater importance of individual genotype than ethnicity in predicting treatment response. 24 A previous study from Germany, extended to HCV genotype 2 and 3 infected patients, also analyzed 200 healthy controls for comparison and reported the frequency of CC, CT, and TT genotypes with 49%, 42.5%, and 8.5%, respectively.…”

Section: Genotyping Of Il28b Polymorphism (Rs12979860c/t)mentioning

confidence: 94%

The Distribution of Genotype and Allelic Frequency of IL28B Gene Polymorphism in Andhra Pradesh, India

Sivaprasad¹,

Rao²,

Gupta³

et al. 2012

Journal of Clinical and Experimental Hepatology

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Section: Genotyping Of Il28b Polymorphism (Rs12979860c/t)mentioning

confidence: 94%

The Distribution of Genotype and Allelic Frequency of IL28B Gene Polymorphism in Andhra Pradesh, India

Sivaprasad¹,

Rao²,

Gupta³

et al. 2012

Journal of Clinical and Experimental Hepatology

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“…[52][53][54][55][56][57][58][59] Two of the articles were abstracts 57,58 linked to full publications. 53,60 All of the included studies report peginterferon and ribavirin combination therapy in patients eligible for shortened treatment duration (i.e. those with specific genotypes as described in Chapter 3, Inclusion crtieria).…”

Section: Quantity and Quality Of Research Availablementioning

confidence: 99%

Peginterferon alfa and ribavirin for chronic hepatitis C in patients eligible for shortened treatment, re-treatment or in HCV/HIV co-infection: a systematic review and economic evaluation

Hartwell

Jones²,

Baxter³

et al. 2011

Health Technol Assess

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address.Paying by credit card You can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume.How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTAPeginterferon alfa and ribavirin for chronic hepatitis C in patients eligible for shortened treatment, re-treatment or in HCV/HIV co-infection: a systematic review and economic evaluation NIHR Health Technology Assessment programmeThe Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a...

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“…En el análisis global de nuestro estudio, la RVS obtenida es más baja que la descrita en la literatura 4,5,15 , lo que hace pensar en factores predictivos adicionales a los descritos para obtener una respuesta terapéutica. Recientemente se han identifi cado factores genéticos fuertemente asociados a la RVS.…”

Section: Discussionunclassified

Resultados del tratamiento con peginterferón alfa-2a y ribavirina en pacientes con hepatitis crónica C

et al. 2011

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Pegylated Interferon‐α‐2a plus Ribavirin for Treatment‐Naive Asian Patients with Hepatitis C Virus Genotype 1 Infection: A Multicenter, Randomized Controlled Trial

Cited by 177 publications

References 37 publications

The Distribution of Genotype and Allelic Frequency of IL28B Gene Polymorphism in Andhra Pradesh, India

The Distribution of Genotype and Allelic Frequency of IL28B Gene Polymorphism in Andhra Pradesh, India

Peginterferon alfa and ribavirin for chronic hepatitis C in patients eligible for shortened treatment, re-treatment or in HCV/HIV co-infection: a systematic review and economic evaluation

Resultados del tratamiento con peginterferón alfa-2a y ribavirina en pacientes con hepatitis crónica C

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