PEG-mesoporous material modified by superparamagnetic nanoparticles as a delivery system of cefotaxime

Salehi, A.; Behpour, Mohsen; Afzali, Daryoush

doi:10.1007/s00203-022-02937-3

Cited by 3 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Mesoporous iron oxide nanoparticles are widely used in the detection of serological substances due to their good biocompatibility and the ability to attach protein or peptide probes. At the same time, due to the magnetic properties of iron oxide, the intermediate pore iron oxide can be magnetically sorted in the production process [56,57]. In addition, in magnetic resonance imaging and magnetic thermotherapy, mesoporous ferric oxide has more advantages than other mesoporous carriers.…”

Section: Mesoporous Iron Oxidementioning

confidence: 99%

Mesoporous Nanoparticles for Diagnosis and Treatment of Liver Cancer in the Era of Precise Medicine

Wang

Zhu

et al. 2022

Pharmaceutics

View full text Add to dashboard Cite

Primary liver cancer is the seventh-most-common cancer worldwide and the fourth-leading cause of cancer mortality. In the current era of precision medicine, the diagnosis and management of liver cancer are full of challenges and prospects. Mesoporous nanoparticles are often designed as specific carriers of drugs and imaging agents because of their special morphology and physical and chemical properties. In recent years, the design of the elemental composition and morphology of mesoporous nanoparticles have greatly improved their drug-loading efficiency, biocompatibility and biodegradability. Especially in the field of primary liver cancer, mesoporous nanoparticles have been modified as highly tumor-specific imaging contrast agents and targeting therapeutic medicine. Various generations of complexes and structures have been determined for the complicated clinical management requirements. In this review, we summarize these advanced mesoporous designs in the different diagnostic and therapeutic fields of liver cancer and discuss the relevant advantages and disadvantages of transforming applications. By comparing the material properties, drug-delivery characteristics and application methods of different kinds of mesoporous materials in liver cancer, we try to help determine the most suitable drug carriers and information media for future clinical trials. We hope to improve the fabrication of biomedical mesoporous nanoparticles and provide direct evidence for specific cancer management.

show abstract

Section: Mesoporous Iron Oxidementioning

confidence: 99%