Peer Review #2 of "No association of COMT with insight problem solving in Chinese college students (v0.1)"

Abstract

Genes involved in dopamine (DA) neurotransmission, such as the catechol-Omethyltransferase gene (COMT), have been suggested as key genetic candidates that might underlie the genetic basis of insight. In a sample of Chinese college students, this study examined whether COMT was associated with individual differences in the ability to solve classic insight problems. The results demonstrated that COMT was not associated with insight problem solving and there was no gender-dependent effect. This study, together with previous studies, raises the possibility of a complex relationship between COMT and insight problem solving.