Pedunculated Malignant Melanoma

“…In our paient, the three main tumors had a common pedicle, which seems to be a unique finding. Since pedunculated malignant melanomas are rare, making a clinical diagnosis is difficult (6, 7). In 1958, Vogler first reported pedunculated melanoma as a more aggressive variant of nodular melanoma (8).…”

Section: Discussionmentioning

confidence: 99%

A Case of Pedunculated Malignant Melanoma of the Vaginal Mucosa

Kimura

Furuya

2001

The Journal of Dermatology

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We report an 84-year-old Japanese woman who presented with a pedunculated malignant melanoma of the vaginal mucosa. Mucosal melanoma is believed to be more common in Japan than other countries, but such tumors of the vulvovaginal region are quite unusual. In our patient, three tumors were connected by a narrow pedicle. Three black tumors measuring 5-10 mm in diameter with a common pedicle were seen on the vaginal mucosa at five o'clock from the cervix. The tumors were hanging from the narrow pedicle. On histologic examination, they were diagnosed as malignant melanoma. Resection was done with a distal margin of 3 cm from the tumors and a margin of 1 cm from the cervix. The patient has had no evidence of local recurrence or distant metastasis. In our patient, the three main tumors had a common pedicle, which seems to be a unique finding. Since pedunculated malignant melanomas are rare, making a clinical diagnosis is difficult. Although pedunculated melanomas are recognized as having a high malignant potential because these lesions are generally thick, a relatively good outcome is sometimes reported. In our patient, there was no tumor infiltration into the dermis of the pedicle, and this may be one reason for the good outcome at present. There has been no previous report of a mucosal melanoma consisting of three tumors like those in the present patient.

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“…However, the nodular appearance can at times result from the uncommon types of MM such as polypoid or pedunculated melanoma. Such lesions can mimic benign skin lesions including intradermal nevus, fibroepithelial polyp, or pyogenic granuloma (1,7,8). On the other hand, SSM usually begins as a smooth or slightly elevated pigmented spot.…”

Section: Di̇scussi̇onmentioning

confidence: 99%

Macular-appearing Nodular melanoma Arising from a Preexisting Melanocytic nevus in an Elderly patient--Can “Older Age of Nevus” be Besponsible for Unusual Morphogenesis and Melanomagenesis?

Taş¹,

Saydam²,

Sagir³

et al. 2016

West Indian Med J

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Malignant melanoma (MM) is the most serious skin tumor whose classical clinical types include lentigo maligna (LM), superficial spreading melanoma (SSM), nodular (NM), and acral lentiginous melanoma (ALM). Clinical appearance of a MM may not always be compatible with its histological type, and sometimes it may express itself with an unusual appearance. We report a 80-year-old man with a NM having a macular appearance, which arose from an acquired melanocytic nevus. The lesion of our patient resembled an SSM clinically, but its histopathological examination proved a NM. Such macular appearance of a NM is an unusual condition. Our case was presented to draw attention to both the misleading macular appearance of the NM, and its unusual nonhierarchical development.

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Pedunculated Malignant Melanoma

Abstract: Pedunculated melanoma is a rare type of melanoma. Conventional staging methods for melanoma may not be reliable in this type of tumor. Complete workup, possibly including sentinel lymph node dissection, should be performed in all patients with pedunculated melanomas.

Cited by 13 publications

References 7 publications

Malignant melanoma: prevention, early detection, and treatment in the 21st century

Malignant melanoma: prevention, early detection, and treatment in the 21st century

A Case of Pedunculated Malignant Melanoma of the Vaginal Mucosa

Macular-appearing Nodular melanoma Arising from a Preexisting Melanocytic nevus in an Elderly patient--Can “Older Age of Nevus” be Besponsible for Unusual Morphogenesis and Melanomagenesis?

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