Pedunculated exogastric leiomyoblastoma presenting as a wandering abdominal mass

Rha, S.E.; Sohn, Kyung-Rak; Lee, S. Y.; Jung, H.; Park, S. M.; Kim, K. M.

doi:10.1007/s002610000088

Cited by 5 publications

(1 citation statement)

References 4 publications

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“…Lesions that should be considered in the differential diagnosis of a cystic abdominal mass on radiologic imaging (CT and MRI) include gastric or bowel duplication cysts, cystic mesothelioma, cystic lymphangioma, cystic mucinous retroperitoneal tumors, cystic pancreatic tumors, pseudocysts of the pancreas or peritoneum, cystic teratoma, and GIST [12–14]. …”

Section: Discussionmentioning

confidence: 99%

Unusual Appearance of a Pendulated Gastric Tumor: Always Think of GIST

Vogelaere

Meert

Vandenbroucke

et al. 2012

Case Reports in Surgery

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Objective. To investigate the clinicopathological characteristics of gastrointestinal stromal tumor (GIST) with significant cystic changes and to assess the molecular genetic characteristics. Methods. In a 68-year-old man, a large abdominal tumoral mass was discovered incidentally. Computed tomography (CT) and magnetic resonance imaging (MRI) confirmed the presence of a large cystic lesion with multiple contrast-enhancing septae and papillary projections. No clear connection with any of the surrounding organs was identified. Malignancy could not be excluded, and surgery was indicated. During surgery, the large mass was found to be attached by a narrow stalk to the large curvature of the stomach. Results. The histological features and immunohistiochemical profile of the tumor cells (positivity for CD117 and CD34) were consistent with a gastrointestinal stromal tumor with a high risk of progressive disease according to the Fletcher classification. Diagnosis was confirmed by mutational analysis; this demonstrated mutation in exon 14 of PDGFRA. During the followup of 97 months, the patient had a cancer-free survival. Conclusions. This case demonstrates that gastrointestinal stromal tumors (GISTs) with extensive cystic degeneration should be considered in the differential diagnosis of a cystic abdominal mass.

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Section: Discussionmentioning

confidence: 99%