Pedobarography: a novel approach to test the efficacy of treatments for lameness; an experience with mavacoxib in dogs with elbow osteoarthritis

Self Cite

Osteoarthritis (OA) is one of the most significant joint diseases worldwide. There are different therapies for OA treatment, and a relatively new strategy is the use of plasma rich in growth factors (PRGF), a platelet rich plasma (PRP) derivative. The objective of this study was to objectively assess the efficacy and duration of the effect of an intraarticular injection of PRGF and a combination of PRGF + physical therapy. The objective assessment was provided using a force platform. The obtained parameters were peak vertical force (PVF) and vertical impulse (VI). A total of 24 dogs with lameness and pain associated to OA attributable to bilateral hip dysplasia were included in the study. Animals were divided into two study groups and evaluated at baseline and at 30, 90, and 180 days after intraarticular PRGF or PRGF + physical therapy. Significant differences were observed at every checkpoint with respect to basal time in both groups. However, after 180 days, the PRGF group showed a decrease in PVF and VI with respect to the values obtained at 90 days. However, the PRGF + physical therapy group maintained increased values of both PVF and VI values during the 180-day study period.

Section: Discussionmentioning

confidence: 55%

Objective Comparison between Platelet Rich Plasma Alone and in Combination with Physical Therapy in Dogs with Osteoarthritis Caused by Hip Dysplasia

Cuervo

Rubio

Chicharro

et al. 2020

Self Cite

“…Although data concerning COP sway and mediolateral imbalance were acquired during walking, they were not quantified. Nonetheless, the authors found clear evidence for postural adjustments and joint instability, as well as their improvement after treatment with mavacoxib [25].…”

Section: Introductionmentioning

confidence: 92%

Center of Pressure in the Paws of Clinically Sound Dogs in Comparison with Orthopedically Diseased Dogs

Reicher

Tichy

Bockstahler

2020

The center of pressure (COP) is recognized as a valuable tool for the assessment of orthopedic and neurologic disorders in humans. Relatively few studies are available in veterinary medicine, particularly concerning the COP in the individual paw. This study assessed the dynamic paw COP parameters during the stance phase of dogs with cox- or cubarthrosis (20 dogs each), as well as of 20 sound dogs. Data were obtained by walking over a pressure platform and analyzed within the diseased groups in comparison to the control group. Both diseased groups showed significant differences between the affected and non-affected limbs, but also in comparison to the reference limbs of sound animals. For coxathrosis, the primary increase was in the medio-lateral COP displacement and the COP area in both hind limbs. For cubarthrosis, the most prominent changes were an increase in the medio-lateral COP displacement in the ipsilateral hind limb and in the cranio-caudal COP displacement in the lame limb. Additionally, the COP area increased in both hind limbs. This can reflect a compensatory redistribution of the body mass as well as compensatory changes of body balance.

“…The most common techniques for gait analysis are force plates (FP) and pressure plates (PP) [ 9 , 14 ]. While the use of FP is recognized as the gold standard [ 8 , 12 , 13 , 15 , 16 , 17 , 18 , 19 ], the use of PP has become increasingly evident in recent years [ 9 , 12 , 13 , 14 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ], to determine and compare the pressure distribution between limbs [ 18 , 19 , 25 , 26 ], as well as the analysis of the VFD on the paws and pads of the sound [ 12 , 20 , 21 , 22 ] and diseased animals [ 13 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Vertical Force Distribution in the Paws of Dogs with Coxarthrosis and Sound Dogs Walking over a Pressure Plate

Moreira

Tichy

Bockstahler

2020

In the present study, we used a pressure plate to investigate the ground reaction forces of limbs and the vertical force distribution (VFD) within the paws of dogs with coxarthrosis. We included 23 sound dogs (GSou) and 23 dogs with hip osteoarthrosis (GCox). The dogs walked over a pressure plate and the peak vertical force (PFz), vertical impulse (IFz) as the percentage of the total force, and time of occurrence of PFz as a percent of the stance phase duration (TPFz%) were evaluated, as well for the entire limb as in the paws (where the paws were divided into four quadrants). The GCox presented a lower PFz% in the lame hind limb than in others and transferred the weight to the caudal quadrants of the front limbs. IFz% was lower in the lame limb and was counterbalanced through higher loading of the caudal quadrants in all unaffected limbs. TPFz% was reached later in the lame limb than in the contralateral limb and the GSou, specifically in the caudomedial quadrant. In conclusion, we found complex compensatory effects of lameness in the hind limb, and this methodology was useful to define the VFD within the paws of dogs.