2018
DOI: 10.1002/pbc.27225
|View full text |Cite
|
Sign up to set email alerts
|

Pediatric superior vena cava syndrome: An evidence‐based systematic review of the literature

Abstract: Superior vena cava syndrome (SVCS) results in vascular, respiratory, and neurologic compromise. A systematic search was conducted to determine the prevalence of pediatric SVCS subtypes and identify clinical characteristics/treatment strategies that may influence overall outcomes. Data from 101 case reports/case series (142 patients) were analyzed. Morbidity (30%), mortality (18%), and acute complications (55%) were assessed as outcomes. Thrombosis was present in 36%, with multi-modal anticoagulation showing im… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
32
0
3

Year Published

2019
2019
2024
2024

Publication Types

Select...
6
3

Relationship

0
9

Authors

Journals

citations
Cited by 36 publications
(36 citation statements)
references
References 17 publications
(47 reference statements)
0
32
0
3
Order By: Relevance
“…A prospective study conducted by Hartmann et al 31 In our study, 72% were extremely preterm and 81% had vena cava syndrome, which in the neonate period is associated with a higher rate of complications due to limited physiological reserve, leading to increased morbidity and mortality in these patients. 52 Furthermore, in 33% of the cases Staphylococcus aureus, one of the most deadly agents in developing countries and a master manipulator of the human coagulation system, 53 was isolated in blood cultures.…”
Section: Discussionmentioning
confidence: 99%
“…A prospective study conducted by Hartmann et al 31 In our study, 72% were extremely preterm and 81% had vena cava syndrome, which in the neonate period is associated with a higher rate of complications due to limited physiological reserve, leading to increased morbidity and mortality in these patients. 52 Furthermore, in 33% of the cases Staphylococcus aureus, one of the most deadly agents in developing countries and a master manipulator of the human coagulation system, 53 was isolated in blood cultures.…”
Section: Discussionmentioning
confidence: 99%
“…With a morbidity of 30% and a mortality of 18%, thromboembolic disorders have a profound impact on public health; they can cause pulmonary embolism (6-8%) and postthrombotic syndrome (12-19%) and have a significant percentage of recurrence (10-20%). (18) In this scenario, and taking into account that treatment in the pediatric population has not yet been clearly established, it is important to make a risk-benefit comparison to define the best therapy for each patient based on antithrombotic and anticoagulant therapeutic options, especially for the neonatal population. In this sense, it is necessary to stress the importance of conducting therapeutic research in this age group to support the therapies described in medical practice, since the lack of evidence has led to the need to extrapolate valid recommendations in the adult population without adequate consensus.…”
Section: Discussionmentioning
confidence: 99%
“…5 One of the most common forms of presentation is Superior Vena Cava Syndrome, whose clinical features may include head and neck edema, dyspnea, cough, neurological symptoms, pleural effusion, or chylothorax. 6 Congenital stenosis of the IVC is also very rare (0.15% of the general population) and may present with an array of clinical findings, ranging from a complete absence of symptoms to lifethreatening conditions, such as portal hypertension or hepatic cirrhosis. 7 Spontaneous lower extremity deep venous thrombosis, leg In this patient, in spite of a not quite impressive clinical presentation, a severe systemic venous drainage stenosis was found, with major involvement of the SVC, mild involvement of the IVC, and otherwise normal intracardiac anatomy.…”
Section: Discussionmentioning
confidence: 99%