Pediatric risk of mortality III score – Predictor of mortality and hospital stay in pediatric intensive care unit

Abstract

Background: Pediatric Risk of Mortality (PRISM) III score is one of the widely used scoring systems to quantify critical illness in the pediatric age group. This study was carried out to find the association of PRISM III score with the outcome (discharge/mortality) and also hospital stay in survivors and nonsurvivors. Setting: The study was conducted in a tertiary care hospital from January 2014 to June 2015. Materials and Methods: A total of 524 patients were admitted, and after excluding the patients who met the exclusion criteria, 486 patients were analyzed. Statistical Analysis: Logistic regression was used to find the association of variables under the PRISM III score with mortality. Linear regression was used to find the association of PRISM III score with length of stay. Results: Mortality was 31%; male: female ratio was 1.5:1. Maximum patients presented with respiratory system involvement (26.3%), and maximum mortality (20.3%) was observed in the patients with respiratory involvement. Discrimination by the model between mortality and survival was excellent (receiver operating characteristic curve [0.903]). Maximum risk of mortality was noticed in mechanically ventilated patients (odds ratio [OR]: 10.87) followed by lower systolic blood pressure (OR: 2.72), deranged prothrombin time, partial thromboplastin time (OR: 1.50), deranged mental status (OR: 1.41), and tachycardia (OR: 1.37). Length of stay (LOS) in patients increased till PRISM III score of 25. Average LOS in survivors was 4.327 days which was not accounted by difference in PRISM III score between different patients. With each unit increase in PRISM III score, LOS increased by 5 h. Conclusions: PRISM III score has excellent capacity to discriminate between survival and mortality. PRISM III score can be used to predict LOS among survivors.

Comparison between paediatric risk of mortality III and paediatric logistic organ dysfunction-2 as mortality predictor in paediatric intensive care

“…The mean PRISM-III was significantly higher in non survivors as compared to survivors. This is similar to studies from Brazil 16 , where the mean scores were 7 and 15, Portugal 10 , where the scores were 5.6 and 19.7 and an Indian study 17 , where the scores were 5.72 and 19.01 among survivors and non survivors respectively. A PELOD-2 score of >15, associated with increased risk of mortality in our study, was also observed in other studies 11 .…”

Meta-Analysis for the Prediction of Mortality Rates in a Pediatric Intensive Care Unit Using Different Scores: PRISM-III/IV, PIM-3, and PELOD-2

“…A total of 29 studies were included for quantitative synthesis, among them, 18 studies that reported on the scoring systems PRISM-III/IV, ( 3 , 4 , 11 , 14 – 21 , 23 – 27 , 37 ), 11 studies that reported data on PIM-3 ( 3 , 4 , 7 , 14 , 16 , 18 , 20 , 28 – 31 ), and nine studies that reported data on PELOD-2 ( 5 , 14 , 16 , 28 , 32 – 36 ). Four studies were reported from India ( 4 , 7 , 17 , 34 ), two from Australia ( 20 , 32 ), two from China ( 20 , 32 ), two from Egypt ( 15 , 18 ), one from Pakistan ( 19 , 26 ), two from Korea ( 14 , 36 ), one from Mexico ( 21 ), one from Singapore ( 28 ), one from UAE ( 29 ), one from Indonesia ( 30 ), one from Africa ( 33 ), one from Saudi Arabia ( 11 ), two from Turkey ( 22 , 24 ), one from Sweden ( 23 ), one from Brazil ( 37 ), one from Switzerland ( 5 ), one from Thailand ( 27 ), one from Italy ( 31 ), and one multi-centric ( 25 ).…”

A prediction model for the efficacy of continuous positive airway pressure on bronchiolitis

“…PRISM III is the most widely used pediatric critical care score. Kaur's study proved that it is capable of accurately determining the severity of the disease and predicting prognosis ( 20 ). Mayordomo-Colunga et al's study found that higher PRISM III was associated with non-invasive ventilation treatment failure ( 21 ).…”