Pediatric Renal Transplantation

Bereket, Gamze; Fine, Richard Ν.

doi:10.1016/s0031-3955(16)40100-8

Cited by 17 publications

(2 citation statements)

References 73 publications

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“…In developed countries, well-functioning renal transplantation continues to result in the best quality of life for patients with ESRF, and therefore dialysis is used most often as a bridge to allow for the care of ESRF patients until such time that they can be transplanted [10][11][12]. However, all forms of RRT are associated with certain problems, complications and even deaths.…”

Section: Renal Replacement Therapymentioning

confidence: 99%

Management of end-stage renal failure

Al-Mosawi¹

2006

Therapy

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Section: Renal Replacement Therapymentioning

confidence: 99%

Management of end-stage renal failure

Al-Mosawi¹

2006

Therapy

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“…This same spirit has permitted the development of several multicenter networks aimed at enhancing research activities and improving the quality of patient care through prospective studies. Among these are the Southwestern Pediatric Nephrology Study Group, the New York-New Jersey Pediatric Nephrology Group, regional groups such as the North American Pediatric Renal Transplantation Cooperative Study (NAPRTCS), and others (58). These groups have published extensively and involve far more patients in clinical and medication trials than possible from single center studies.…”

Section: Research Themes Since 1970mentioning

confidence: 99%

The Development of Pediatric Nephrology

Chesney

2002

Pediatr Res

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The following is the first article in this series. It Pediatric nephrology, as a discipline, arose from descriptive studies of childhood glomerulonephritis in Europe and the field of pediatric metabolism in the United States. While pediatric scientists before 1950 were concerned with fluid and electrolyte metabolism, regulation of intracellular and extracellular fluid, acid-base homeostasis, and parenteral fluid therapy, the defined field of nephrology developed after the Second World War around six major advances: ACTH and glucocorticoid therapy for nephrotic syndrome; renal biopsy to diagnose glomerular disease; the role of immunologic factors in glomerular injury; the use of dialysis as renal replacement therapy; renal transplantation as the optimal form of therapy in children with end stage renal failure; and recognition of renal disease in the etiology of 80% of cases of childhood hypertension. These discoveries led to focused research, the definition of specific training in nephrology, establishment of an American, European, and an International Society of Pediatric Nephrology, as well as an American SubBoard of Pediatric Nephrology, and the inception of a journal, Pediatric Nephrology, now in its 15th year. Major research themes have included developmental nephrology, transplantation immunology, and concerns about growth in children with renal disease. Many clinical entities have been described in detail, some of which are almost confined to children. The scientific basis of pediatric nephrology, ongoing patient care needs, and its technical aspects -renal biopsy, dialysis and transplantationassure its continuing future as a major pediatric discipline on all continents. (Pediatr Res 52: 770-778, 2002) I. THE ORIGINS OF INTEREST IN CHILDHOOD RENAL DISEASES: 1820 -1950The development of the discipline of pediatric nephrology arose from clinical research conducted in the 130-year period from 1820 to 1950. It was during this period that pediatric scientists became interested in the definition of glomerular disorders and in fluid and electrolyte metabolism, the maintenance of normal volume and tonicity and acid-base status, as well as the pathophysiology of such disorders as rickets and diarrhea (1-5) ( Table 1).Pediatric kidney disease was initially considered from a descriptive rather than quantitative perspective. Early treatises on kidney diseases in children were remarkably accurate in terms of their clinical descriptions of various renal disorders, particularly glomerular conditions. In the 11th edition of Eduard Henoch's classic text Kinderkrankheiten (6), he describes

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