Pediatric Problems of Hiv Infection and Solutions in Saint Petersburg

Ястребова, Е. Б.; Самарина, А. В.; Фертих, Е. К.; Гутова, Л. В.

doi:10.22328/2077-9828-2019-11-1-31-37

Cited by 5 publications

(2 citation statements)

References 4 publications

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“…У 3 диагностирована стадия 4А, у 1 -стадия 4В ВИЧ-инфекции. У всех детей данной группы установлено перинатальное инфицирование, с момента постановки диагноза они получали АРВТ в соответствии с Клиническими рекомендациями МЗ РФ, 2017 г. Клинические симптомы, состояния и заболевания у детей с ВИЧ-инфекцией у каждого ребенка в отдельно взятый промежуток времени могут быть различными [2,3,5,16,19]. Среди них выделяют специфические для ВИЧ-ин фицированных детей (пневмоцистную пневмонию, кандидоз пищевода, лимфоидную интерстициальную пневмонию, герпес-зостер-вирусную инфекцию с поражением нескольких дерматомов, саркому Капоши и др.)…”

Section: результаты и обс у ж дениеunclassified

“…Большую проблему для врачей-педиатров представляют ВИЧ-диссиденты, особенно родители, живущие с ВИЧ и отказывающиеся от наблюдения и лечения своих детей. Нередко в отсутствие медицинского наблюдения и лечения у ВИЧ-инфицированных детей происходит прогрессирование заболевания, развитие вторичных заболеваний и осложнений, приводящих к их гибели [18][19][20]. Врачи-педиатры Центра СПИД вынуждены защищать права детей на охрану здоровья, обращаясь с запросами и заявлениями в органы опеки и попечительства, суды, прокуратуры, правоохранительные органы [14,15,[18][19][20].…”

Section: Introductionunclassified

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Contemporary diagnosis of HIV infection in pediatrician’s practice

Hakizimana

Жан-Клод²,

Ivanov

et al. 2020

Pediatr (SPb)

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The objective of the study: evaluation of the effectiveness of clinico-epidemiological and laboratory diagnostics of HIV infection in pediatric practice. Materials and methods. Under the supervision of pediatricians of the Department of motherhood and childhood of the St. Petersburg AIDS Center, there were 388 HIV-infected children aged from one month to 17 years inclusive. Due to the reasons of late detection and HIV dissidence of parents, 18 children (4%) died cumulatively among the children observed in St. Petersburg center for AIDS. The object of the immunohistochemical study was randomly selected HIV-infected children who applied to the center for prevention and control of AIDS for return visits. Material for testing for the presence of HIV-1 P24 antigen was taken from the back wall of the nasopharynx. Results. When analyzing the ways of HIV infection in children registered at the maternity and childhood Department of the Saint Petersburg AIDS Center, it turned out that 363 children were infected perinatally (93,6%), 23 (5,9%) sexually infected and 2 children through injecting drugs (0.5%). The proposed method of immunocytochemistry for the diagnosis of HIV infection in children can find its application, especially for primary diagnostics, which may simplify and reduce the cost of laboratory diagnostics.

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Section: результаты и обс у ж дениеunclassified

Section: Introductionunclassified

Contemporary diagnosis of HIV infection in pediatrician’s practice

Hakizimana

Жан-Клод²,

Ivanov

et al. 2020

Pediatr (SPb)

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Assessing the effectiveness of prevention of mother-to-child HIV transmission

et al. 2021

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Aim. To analyze the outcomes of a set of interventions to prevent vertical transmission of the human immunodeficiency virus (HIV) in the Republic of Mari El. Methods. A retrospective analysis of temporary registration forms Notifications of the termination of pregnancy in an HIV-infected woman and Notifications of a newborn born by an HIV-infected mother, case histories and outpatient medical records of HIV-infected women who gave birth in 20002018 was carried out. The study included all children born in the Republic of Mari El to HIV-positive women registered with the Republican Center for the Prevention and Control of AIDS and Infectious Diseases, as well as children whose HIV status is detected after birth as a result of epidemiological investigations. The assessment of the risks of transmission as an outcome of the three-step preventive interventions has been carried out. A comparative analysis of the results of perinatal prevention of HIV transmission in the Republic of Mari El and other regions of the Russian Federation was performed. Results. A total of 299 HIV-infected pregnant women and 368 children born to these women during the study period were registered in the region; 63 (21.7%) of these women had more than one child. Over the entire study period, 18 (4.8%) children with confirmed HIV infection were registered. The most common factor associated with infant HIV infection is late maternal HIV diagnosis: (1) several years after childbirth in the absence of antiretroviral (ARV) prophylaxis and the infants were breastfeeding (11 cases, 64.7%); (2) during or shortly after childbirth, when the patient did not receive entire three-step antiretroviral prophylaxis during pregnancy and childbirth (6 cases, 29.4%); (3) in the third trimester of pregnancy (1 case, 5.5%). An important limitation for the successful prevention of vertical transmission of HIV was the lack of routine HIV testing, which is required by women and their partners before and at various stages during pregnancy. A single case of self-infection indicates the need to introduce preventive measures from early adolescence among children. Conclusion. Due to the late maternal HIV diagnosis, during or after delivery, HIV transmission events occurred either with limited or no limited antiretroviral prophylaxis.

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Рsychosexual needs and sexual behavior of adolescents living with HIV since infancy

Safonova¹,

Кольцова

2021

VIČ-infekc. immunosupr.

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The first generation of children living with HIV since their infancy are growing up and create a new unique group of patients at AIDS Center. Young adults living all their life with chronicle disease that is stigmatized by the society especially in connection with sexuality, have same sexual and reproductive needs and rights as their HIV-negative peers. Aim of this study was to investigate attitudes, needs and social norms toward reproductive and sexual health among adolescents and young adults living with HIV since infancy, as well as their sexual behavior. Among 27 young males and females of 16–20 years old who have lived with HIV since infancy and who took part in anonymous on-line questionnaire, 50% are sexually active. Most of them didn’t experience restrictions in their sexual and reproductive rights, nevertheless they often feel fear of transmitting HIV sexually to the other person. Adolescents and young adults perinataly infected with HIV are willing to use condom during sex and disclose their HIV status to their partner, however they have difficulties in more «complicated» social situations. They have a need in talking about sexual and reproductive health.

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Pediatric Problems of Hiv Infection and Solutions in Saint Petersburg

Cited by 5 publications

References 4 publications

Contemporary diagnosis of HIV infection in pediatrician’s practice

Contemporary diagnosis of HIV infection in pediatrician’s practice

Assessing the effectiveness of prevention of mother-to-child HIV transmission

Рsychosexual needs and sexual behavior of adolescents living with HIV since infancy

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