Pediatric perianal rhabdomyosarcoma: Multimodal therapy for tumor control

Behera, Saswati; Mahajan, Jai Kumar; Bansal, Deepak

doi:10.1002/pbc.29677

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2023

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“…[13] PRMS is rare and accounts for only 2% of RMS. [14] Some PRMS are misdiagnosed as perianal abscesses that delay treatment leading to local or distant metastasis. [15] Because magnetic resonance imaging indicates that PRMS is more closely associated with the external anal sphincter.…”

Section: Discussionmentioning

confidence: 99%

Perianal rhabdomyosarcoma in an adult: A case report and review of the literature

Yang,

Kong,

Wang

et al. 2023

Medicine

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Perianal/perineal rhabdomyosarcomas (PRMS) is rare, and the outcome is poor. A 29-year-old female presented with perineal rhabdomyosarcomas revealed metastases to inguinal lymph nodes on the bilateral side. Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and bevacizumab for 2 cycles. After 3 cycles of nivolumab, dacarbazine, cisplatin, and vinblastine therapy, a partial response was identified in the patient. The surgical resection was performed. The patient received neoadjuvant chemotherapy before surgery and was weak after surgery, so he did not receive chemoradiotherapy. The patient succumbed after 11 months postoperatively due to widespread intraabdominal metastasis.

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Section: Discussionmentioning

confidence: 99%