Pediatric oncology—The final frontier for extracorporeal membrane oxygenation in children?

Alexander, Peta; Thiagarajan, Ravi R.

doi:10.1002/pbc.28521

Cited by 6 publications

(5 citation statements)

References 19 publications

(43 reference statements)

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“…For example, one small retrospective study reports intracranial bleeding as a cause for ECMO discontinuation in 11% of nonsurvivors with leukemia 7. However, other data display better overall outcomes with similar survival rates in both populations 3,8. Sparse evidence and absent guidelines made clinical decisions difficult in terms of ECMO initiation in acutely deteriorating pediatric oncology patients in the past decade.…”

Section: Discussionmentioning

confidence: 99%

“…7 However, other data display better overall outcomes with similar survival rates in both populations. 3,8 Sparse evidence and absent guidelines made clinical decisions difficult in terms of ECMO initiation in acutely deteriorating pediatric oncology patients in the past decade. That said, in some centers, both malignancy and HSCT remain relative or even absolute contraindications for ECMO.…”

Section: Discussionmentioning

confidence: 99%

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The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia

Nader¹,

Bonde²,

Massaro³

et al. 2022

Journal of Pediatric Hematology/Oncology

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An 18-year-old girl with high-risk acute myeloid leukemia developed Streptococcus mitis septic shock and multiorgan dysfunction syndrome, including biventricular failure. Due to the anticipated reversibility of her cardiogenic shock, her young age, and her favorable survival chance after an allogeneic hematopoietic stem cell transplant, she was placed on full circulatory support with venoarterial extracorporeal membrane oxygenation as a bridge to her successful hematopoietic stem cell transplantation 2 months later. This highlights the importance of prognostication in patient selection for extracorporeal life support. A multidisciplinary approach is essential to each case until more definite initiation criteria, risk stratification, and treatment protocols are established.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia

Nader¹,

Bonde²,

Massaro³

et al. 2022

Journal of Pediatric Hematology/Oncology

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“…Nevertheless, morbidity and mortality of this invasive rescue therapy remain high. As recently stated (19), to offer or withhold ECMO in immunocompromised children with potentially reversible respiratory or cardiorespiratory failure should therefore remain a careful patient-and family-centered decision made with the support of a multidisciplinary expert team.…”

Section: Discussionmentioning

confidence: 99%

Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients

et al. 2021

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Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for severe respiratory and/or circulatory failure. Few data exist on the potential benefit of ECMO in immunocompromised pediatric patients with cancer and/or hematopoietic cell transplantation (HCT). Over a period of 12 years, eleven (1.9%) of 572 patients with new diagnosis of leukemia/lymphoma and nine (3.5%) of 257 patients post allogeneic HCT underwent ECMO at our center. Five (45%) and two (22%) patients, respectively, survived to hospital discharge with a median event-free survival of 4.2 years. Experiences and outcomes in this cohort may aid clinicians and families when considering ECMO for individual patients.

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“…To the Editor, We read with great interest the articles by Steppan et al 1 and Peta et al 2 on extracorporeal membrane oxygenation (ECMO) in children with cancer.…”

Section: Prolonged Extracorporeal Membrane Oxygenation In Pediatric Leukemia With Severe Acute Respiratory Distress Syndrome and Persistementioning

confidence: 99%

Prolonged extracorporeal membrane oxygenation in pediatric leukemia with severe acute respiratory distress syndrome and persistent fungemia

Kebudi

Sözmen

Bahar

et al. 2021

Pediatric Blood & Cancer

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Pediatric oncology—The final frontier for extracorporeal membrane oxygenation in children?

Cited by 6 publications

References 19 publications

The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia

The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia

Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients

Prolonged extracorporeal membrane oxygenation in pediatric leukemia with severe acute respiratory distress syndrome and persistent fungemia

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