Pediatric Norovirus Gastroenteritis in Ireland: Seasonal Trends, Correlation with Disease Severity, Nosocomial Acquisition and Viral Co-Infection

Barsoum, Zakaria

doi:10.1007/s12098-020-03540-4

Cited by 3 publications

(3 citation statements)

References 22 publications

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“…Norovirus is detected throughout the year, with the autumn and winter seasons observed to report a higher frequency of cases [ 31 , 36 , 37 ]; the detection rate of norovirus cases correlates positively with humidity [ 37 ]. Co-infection with rotavirus [ 38 , 39 ], astrovirus [ 40 ], and Salmonella [ 39 ] may occur in certain cases. Norovirus infections are observed to cause more severe symptoms of gastroenteritis in children compared with rotavirus, especially after the introduction of the rotavirus vaccination period [ 41 ].…”

Section: Causative Agents Of Agementioning

confidence: 99%

Acute Infectious Gastroenteritis: The Causative Agents, Omics-Based Detection of Antigens and Novel Biomarkers

et al. 2021

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Acute infectious gastroenteritis (AGE) is among the leading causes of mortality in children less than 5 years of age worldwide. There are many causative agents that lead to this infection, with rotavirus being the commonest pathogen in the past decade. However, this trend is now being progressively replaced by another agent, which is the norovirus. Apart from the viruses, bacteria such as Salmonella and Escherichia coli and parasites such as Entamoeba histolytica also contribute to AGE. These agents can be recognised by their respective biological markers, which are mainly the specific antigens or genes to determine the causative pathogen. In conjunction to that, omics technologies are currently providing crucial insights into the diagnosis of acute infectious gastroenteritis at the molecular level. Recent advancement in omics technologies could be an important tool to further elucidate the potential causative agents for AGE. This review will explore the current available biomarkers and antigens available for the diagnosis and management of the different causative agents of AGE. Despite the high-priced multi-omics approaches, the idea for utilization of these technologies is to allow more robust discovery of novel antigens and biomarkers related to management AGE, which eventually can be developed using easier and cheaper detection methods for future clinical setting. Thus, prediction of prognosis, virulence and drug susceptibility for active infections can be obtained. Case management, risk prediction for hospital-acquired infections, outbreak detection, and antimicrobial accountability are aimed for further improvement by integrating these capabilities into a new clinical workflow.

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Section: Causative Agents Of Agementioning

confidence: 99%

Acute Infectious Gastroenteritis: The Causative Agents, Omics-Based Detection of Antigens and Novel Biomarkers

et al. 2021

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“…En niños menores de cinco años, la diarrea es una causa frecuente de hospitalización; los patógenos virales representan 93% de los casos, 29% corresponde a norovirus. 1,2 El primer brote se describió en Norwalk, Ohio en 1972 y se trata de un virus ARN de la familia Caliciviridae. 2,3 La transmisión se produce vía fecal-oral, con un periodo de incubación de 24 a 48 horas, siendo la excreción máxima durante las 24 a 48 horas después de la enfermedad.…”

Section: Introductionunclassified

“…1,2 El primer brote se describió en Norwalk, Ohio en 1972 y se trata de un virus ARN de la familia Caliciviridae. 2,3 La transmisión se produce vía fecal-oral, con un periodo de incubación de 24 a 48 horas, siendo la excreción máxima durante las 24 a 48 horas después de la enfermedad. 3…”

Section: Introductionunclassified

Sangrado de tubo digestivo alto asociado a infección gastrointestinal por norovirus

Mayén¹,

Haro²,

Haro³

et al. 2022

Acta Médica Grupo Ángeles

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Introducción: Norovirus es uno de los principales agentes infecciosos causantes de enfermedades diarreicas agudas a nivel mundial. El cuadro clínico habitual por este agente se caracteriza por vómitos y diarreas acuosas; sin embargo, en los últimos años, en la literatura se han reportado nuevas variantes o subtipos de norovirus, en las cuales se han descrito diferentes presentaciones clínicas, así como complicaciones tanto intestinales como extraintestinales. Reporte de caso: En este trabajo se describe el caso de un lactante que inicia con un cuadro agudo de vómito de contenido gastroalimentario y "pozos de café", que evolucionó hacia una intolerancia a la vía oral y deshidratación. Requirió hidratación intravenosa así como vigilancia hospitalaria. Se realizó un panel molecular gastrointestinal que reportó norovirus. Conclusiones: La infección por norovirus es una causa frecuente de gastroenteritis en niños, en la mayoría de casos los síntomas se limitan a manifestaciones intestinales; sin embargo, a través de los años se han descrito manifestaciones poco frecuentes asociadas a la presencia del virus. Con el avance en la detección molecular se ha relacionado la presencia de sangrado de tubo digestivo alto a la presencia del virus; considerar esta relación es determinante para identificar y tratar de forma oportuna este tipo de complicaciones.

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Study of Seasonal and Regional Prevalence of Norovirus in Children: A Step Towards Disease Control

Bolia

Srivastava

2021

Indian J Pediatr

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Pediatric Norovirus Gastroenteritis in Ireland: Seasonal Trends, Correlation with Disease Severity, Nosocomial Acquisition and Viral Co-Infection

Cited by 3 publications

References 22 publications

Acute Infectious Gastroenteritis: The Causative Agents, Omics-Based Detection of Antigens and Novel Biomarkers

Acute Infectious Gastroenteritis: The Causative Agents, Omics-Based Detection of Antigens and Novel Biomarkers

Sangrado de tubo digestivo alto asociado a infección gastrointestinal por norovirus

Study of Seasonal and Regional Prevalence of Norovirus in Children: A Step Towards Disease Control

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