Pediatric Meckel's Diverticulum: Report of 208 Cases and Review of the Literature

Francis, Adero; Kantarovich, Diana; Khoshnam, Nasim; Alazraki, Adina; Patel, Binita; Shehata, Bahig M.

doi:10.3109/15513815.2016.1161684

Cited by 51 publications

(35 citation statements)

References 8 publications

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“…Most patients with symptomatic or resected Meckel's are male. The largest retrospective patient series (each containing >100 patients) report a male to female gender ratio of 1.5:1 to 4:1 (see Table 3, [12–18,20,21] ). The same is true for the database queries performed by Alemayehu et al [14] and Ruscher et al [16]…”

Section: Resultsmentioning

confidence: 99%

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Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century

Hansen

Søreide²

2018

Medicine

205

261

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Section: Resultsmentioning

confidence: 99%

“…Present in 4.6% to 71.0% of symptomatic Meckel's, gastric tissue is the most common, followed by pancreatic tissue present in 0% to 12.0%, see Table 5. [13,17,18,20,21,23,24,26,28,35,38,39,41] Articles are included in Table 5 if they differentiated between symptomatic and silent Meckel's and number of patients were >50.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century

Hansen

Søreide²

2018

Medicine

205

261

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“…Other studies reported a 1.2–2% complication risk after MD resection compared with a lifetime morbidity risk 6.4–7% and recommended resection of all MDs encountered . The reported association of MD with intestinal cancer in adulthood impelled the tendency towards resection …”

Section: Discussionmentioning

confidence: 99%

Predictive model of heterotopy in Meckel's diverticulum in children

Sinopidis

Fouzas

Kambouri

et al. 2019

ANZ Journal of Surgery

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Background:The presence of heterotopic tissue in Meckel's diverticulum (MD) increases the incidence of future complications. Based on this concept, this study aimed to detect clinical and morphological parameters able to predict the probability of heterotopy in incidentally discovered uncomplicated MD and to develop a risk-based classification tool. Methods: The clinical records of 146 patients who underwent MD resection were reviewed. MD complications (bleeding, inflammation, perforation or involvement in pathological processes such as intussusception) and MD dimensions (width, length and the product width × length) were evaluated in association with heterotopy. Regression analysis was used to explore the discrete effect of clinically relevant parameters, which were subsequently combined in a Classification and Regression Tree. Results: The probability of heterotopy was higher in complicated MDs. The width of the base of the MD and the product width × length were also significant predictors of heterotopy. A stepwise combination (Classification and Regression Tree model) of (i) uncomplicated macroscopic presentation, (ii) width <2.5 cm, (iii) age <10 years and (iv) product width × length <4 cm 2 resulted in a null probability of heterotopy in our study group. Conclusion: The combination of MD-related clinical and morphological parameters using advanced statistical tools may assist in estimating the probability of heterotopy. This may be applied in incidentally discovered uncomplicated MDs during abdominal surgery for other morbidities. Prospective studies are required to confirm our findings and test the practical usefulness of the classification tool developed here. © 2019 Royal Australasian College of Surgeons ANZ J Surg 89 (2019) E241-E245ANZJSurg.com

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“…5 According to Rho et al, the chief complaints were GI bleeding and nonspecific abdominal symptoms whereas some study mentions intestinal obstruction as the major presentation. [6][7][8] It is seen that bleeding and intussusception due to MD were more frequent in children under two years of age, whereas symptoms of intestinal obstruction occur more often after two years. 9 Rattan et al, mentioned intestinal obstruction (86%) was the most common presentation for MD.…”

Section: Discussionmentioning

confidence: 99%

Diverse Presentation of Meckel’s Diverticulum in Pediatric Patients

Kumar

Jalan

Patowary

et al. 2018

J Coll Med Sci-Nepal

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IntroductionMeckel’s Diverticulum is the most common congenital disease and seen in 2% of population. It is difficult to diagnose preoperative, mostly seen during operation with its various presentation.Material and Methods This is a retrospective study in which all the cases diagnosed as Meckel’s diverticulum with its complication diagnosed while doing operation were included. Demographic data, clinical presentation, preoperative diagnosis, intraoperative findings, surgical procedure performed, histopathological report and postoperative follow up of patients were recorded and statistically analyzed. The aim of this study was to assess various presentation of Meckel’s diverticulum in 8 years of duration in college of medical sciences, Bharatpur Nepal. ResultsOut of 32 cases, there were 20 male and 12 female with M:F ratio1.66:1. The mean age was 8.34 ± 3.98 years. All together sixteen (50%) patients had features intestinal obstruction. Perforation was seen in 28.1% patients, intussusception in 21.8%, diverticulitis in 15.6%, small bowel volvulus around fibrous band in 18.8%, internal herniation in 9.4% and massive bleeding in 6.3% patients. The average distance from ileocecal junction was 40-60 cm. All cases underwent emergency laparotomy, presence of Meckel’s diverticulum was incidental intraoperative finding. Three cases had superficial wound infection. Small intestine mucosa followed by gastric, pancreatic and colonic mucosa were most common histological finding. The average duration of hospital stay was 5 to 8 days.ConclusionMeckel's Diverticulum is a true diverticular anomaly that may remain clinically silent for lifetime, or it may have life-threatening complications. Due to nonspecific features in case of acute abdomen, Meckel’s diverticulum and its complications should be kept as an important differential diagnosis.Keywords: intestinal obstruction; meckel’s diverticulum; volvulus.

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Pediatric Meckel's Diverticulum: Report of 208 Cases and Review of the Literature

Cited by 51 publications

References 8 publications

Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century

Systematic review of epidemiology, presentation, and management of Meckel's diverticulum in the 21st century

Predictive model of heterotopy in Meckel's diverticulum in children

Diverse Presentation of Meckel’s Diverticulum in Pediatric Patients

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