Pediatric laryngeal sarcoma: Systematic review and pooled analysis

Pediatric laryngeal embryonal rhabdomyosarcoma

“…Rhabdomyosarcoma is the most common soft tumor in children, mainly located at the head and neck region, followed by genitourinary tract and extremities. 4 Our patient presented laryngeal symptoms (progressive hoarseness and dyspnea) due to this well-defined supraglottic nodular lesion. This presentation is extremely unusual, since the sites mainly affected in head and neck region are the orbits, parameningeal sites (nasopharynx, nose, sinuses, temporal bone, pterygopalatine fossa, and infratemporal fossa) and the non-parameningeal sites.…”

“… 5 The larynx is affected in less than 3% of head and neck rhabdomyosarcomas 6 and, according to a systematic review, only 37-cases have been documented, none of them in Brazil. 4 In the literature, the laryngeal rhabdomyosarcoma is reported to have a better outcome than in other sites at the head and neck, due to early diagnosis and surgical access. 7 …”

Total laryngectomy in neonate with laryngeal sarcoma: perioperative management: Case report

“…On the other hand, the patients who received bimodal therapy were distributed as follows: chemo and radiotherapy (17.2%), surgery and chemotherapy (10.3%), surgery and radiotherapy (20.7%) and the rest of the patients were treated with surgery, chemotherapy, and radiotherapy (27.6%). Among all patients who underwent initial removal or ablation surgeries, 50% underwent total laryngectomy, while the other 50% had laryngeal preservation procedures such as partial laryngectomy or endoscopic resection of the laryngeal lesion [19].…”