Pediatric Knee Osteochondritis Dissecans Lesions

Cruz, Aristides I.; Shea, Kevin G.; Ganley, Theodore J.

doi:10.1016/j.ocl.2016.05.001

Cited by 41 publications

(40 citation statements)

References 69 publications

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“…28, 29 (33, 34) Both increased activity in males combined with the possibility of increased traumatic events can result in repetitive loading and micro-trauma, which have been shown to be a risk factor for OCD lesions. (5, 6, 8, 9) Lastly, emerging studies have revealed genetics to be an important component and may also contribute to the increased risk in males compared to females. (8, 35, 36)…”

Section: Discussionmentioning

confidence: 99%

“…(5, 6, 8, 9) Lastly, emerging studies have revealed genetics to be an important component and may also contribute to the increased risk in males compared to females. (8, 35, 36)…”

Section: Discussionmentioning

confidence: 99%

“…This decrease likely represents the fact that in young patients with open growth plates, OCD lesions have a great capacity to heal and these lesions may be more amenable to nonoperative management. (8, 43) One study reported that up to two-thirds of all stable lesions in skeletally immature patients heal at 6-months of follow-up after activity modification and immobilization. (44) Other studies have reported similar results with younger age associated with superior outcomes such as improved healing rates.…”

Section: Discussionmentioning

confidence: 99%

“…(4–7) Additionally, repetitive microtrauma, genetic predisposition, and endocrine abnormalities can also be associated with OCD lesions. (8–11) While most commonly diagnosed in pediatric patients, symptomatic OCD lesions can also be found in the adult knee and likely represents undiagnosed adolescent lesions. (10, 12–16)…”

Section: Introductionmentioning

confidence: 99%

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Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population-based study in Olmsted County

Pareek

Sanders

et al. 2017

Osteoarthritis and Cartilage

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Objective To (1) define the population-based incidence of OCD lesions of the knee using the population of Olmsted County, (2) examine trends over time, and (3) evaluate changes in the rate of surgical management. Method The study population included 302 individuals who were diagnosed with knee OCD lesions between January 1, 1976 and December 31, 2014. The complete medical records were reviewed to confirm diagnosis and to extract injury and treatment details. Age- and gender-specific incidence rates were calculated and adjusted to the 2010 US population. Poisson regression analyses were performed to examine incidence and surgery trends by age, gender, and calendar period. Results The overall age- and gender-adjusted incidence annual incidence of knee OCD lesions was 6.09 per 100,000 person-years. The incidence was significantly higher (P<0.001) in males (8.82, 95% CI 7.63 to 10.00 per 100,000) compared to females (3.32, 95% CI 2.61 to 4.04 per 100,000). Age- and gender-specific incidence was highest in both males and females in the 11–15 years old at 39.06 and 16.15 per 100,000, respectively. In males aged 11 to 15 years, OCD incidence increased significantly over the study period from 20.68 in 1976–1985 to 48.16 in 2006–2014 (per 100,000). Conclusions The overall age- and gender-adjusted annual incidence of knee OCD lesions in the Olmsted Country Population was 6.09 per 100,000 person-years with a significantly higher incidence in males compared to females. The highest incidence for both males and females occurred between the ages 11 to 15 years. Trends indicate increasing OCD incidence in younger males and decreasing surgical management in females over the last decade.

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Section: Discussionmentioning

confidence: 99%

“…(5, 6, 8, 9) Lastly, emerging studies have revealed genetics to be an important component and may also contribute to the increased risk in males compared to females. (8, 35, 36)…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incidence of symptomatic osteochondritis dissecans lesions of the knee: a population-based study in Olmsted County

Pareek

Sanders

et al. 2017

Osteoarthritis and Cartilage

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show abstract

“…While we suspect that trauma may have a role in the development of OCD, we also know that many patients with OCD do not have a definable traumatic event, and many of those who do report trauma have a contralateral lesion that cannot be linked to trauma and is frequently asymptomatic [2,3]. Overuse is also suspected to play a role, but studies examining this role are lacking [1].…”

mentioning

confidence: 99%