Pediatric Invasive Gastrointestinal Fungal Infections: Causative Agents and Diagnostic Modalities

El‐Shabrawi, Mortada; Madkour, Lamiaa A.; Voigt, Naglaa

doi:10.9734/mrji/2017/32231

Cited by 2 publications

(2 citation statements)

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“…Basidiobolomycosis is known for its burden in countries of the African continent ( El-Shabrawi et al, 2017 ). In any case, the infection has been reported in several countries with tropical and subtropical climates ( Figure 3A , Suppl.…”

Section: Difference Between Risk Factors and Affected Populations In ...mentioning

confidence: 99%

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences

Acosta-España

Voigt

2022

Front. Microbiol.

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Fungal diseases were underestimated for many years. And the global burden of fungal infections is substantial and has increased in recent years. Invasive fungal infections have been linked to several risk factors in humans which basically depend on the individual homeostasis of the patients. However, many fungi can infect even apparently healthy people. Knowledge of these pathogens is critical in reducing or stopping morbidity and/or mortality statistics due to fungal pathogens. Successful therapeutic strategies rely on rapid diagnosis of the causative fungal agent and the underlying disease. However, the terminology of the diseases was updated to existing phylogenetic classifications and led to confusion in the definition of mucormycosis, conidiobolomycosis, and basidiobolomycosis, which were previously grouped under the now-uncommon term zygomycosis. Therefore, the ecological, taxonomic, clinical, and diagnostic differences are addressed to optimize the understanding and definition of these diseases. The term “coenocytic hyphomycosis” is proposed to summarize all fungal infections caused by Mucorales and species of Basidiobolus and Conidiobolus.

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Section: Difference Between Risk Factors and Affected Populations In ...mentioning

confidence: 99%

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences

Acosta-España

Voigt

2022

Front. Microbiol.

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“…is poorly understood. Basidiobolomycosis develops in the subcutaneous soft tissue and yet can involve muscles and surrounding organs, as well as gastrointestinal lesions [ 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Subcutaneous Granulomatous Inflammation due to Basidiobolomycosis: Case Reports of 3 Patients in Buruli Ulcer Endemic Areas in Benin

Brun

Roux

Sopoh³

et al. 2018

Case Reports in Pathology

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Background Basidiobolomycosis is a rare subcutaneous mycosis, which can be mistaken for several other diseases, such as soft tissue tumors, lymphoma, or Buruli ulcer in the preulcerative stage. Microbiological confirmation by PCR for Basidiobolus ranarum and culture yield the most specific diagnosis, yet they are not widely available in endemic areas and with varying sensitivity. A combination of histopathological findings, namely, granulomatous inflammation with giant cells, septate hyphal fragments, and the Splendore-Hoeppli phenomenon, can confirm basidiobolomycosis in patients presenting with painless, hard induration of soft tissue. Case Presentations We report on three patients misdiagnosed as suffering from Buruli ulcer, who did not respond to Buruli treatment. Histopathological review of the tissue sections from these patients suggests basidiobolomycosis. All patients had been lost to follow-up, and none received antifungal therapy. On visiting the patients at their homes, two were reported to have died of unknown causes. The third patient was found alive and well and had experienced local spontaneous healing. Conclusion Basidiobolomycosis is a rare subcutaneous fungal disease mimicking preulcerative Buruli ulcer. We stress the importance of the early recognition by clinicians and pathologists of this treatable disease, so patients can timely receive antifungal therapy.

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Pediatric Invasive Gastrointestinal Fungal Infections: Causative Agents and Diagnostic Modalities

Cited by 2 publications

References 54 publications

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences

Subcutaneous Granulomatous Inflammation due to Basidiobolomycosis: Case Reports of 3 Patients in Buruli Ulcer Endemic Areas in Benin

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