Pediatric Head and Neck Malignancies

Abstract

The incidence of head and neck malignancies among children younger than 15 years in the United States from 1973 through 1996 increased at a greater rate than childhood cancer in general.

Pediatric Oral/Maxillofacial Soft Tissue Sarcomas: A Clinicopathologic Report of Four Cases

“…The broad differential diagnosis of lesions in the OMF region is described in table 1 . The rarity of STS in this region and the preponderance of RMS noted at our institution are consistent with data from larger epidemiological studies [ 3 ]. Pathology showed overlapping poorly differentiated features, demonstrating the importance of immunohistochemistry and molecular testing in confirming the diagnoses.…”

Pediatric Oral/Maxillofacial Soft Tissue Sarcomas: A Clinicopathologic Report of Four Cases

“…The broad differential diagnosis of lesions in the OMF region is described in table 1 . The rarity of STS in this region and the preponderance of RMS noted at our institution are consistent with data from larger epidemiological studies [ 3 ]. Pathology showed overlapping poorly differentiated features, demonstrating the importance of immunohistochemistry and molecular testing in confirming the diagnoses.…”

Spectrum of head and neck cancer in children

“…Head and neck cancers were most frequent among teenagers 15–18 years old (39%), followed by children 4 years or younger (27%), 10–14 years (21%), and 5–9 years (13%). [4] The overall sex ratio in favor of the males was comparable with the studies where the male:female ratio were 1.5:1[5] and 1.16:1. [11] However, in the latter study incidence increased in girls with age and exceeded that of boys in the age group between 10 and 14 years.…”

Pediatric Head and Neck Malignancies in the United States: A 20‐Year Population‐Based Study

“…Thyroid was the most common primary site accounting for 38.4% of all tumors. This was a large increase from Albright's findings of 22.1% [3]. When only including the ages of <1-19 years, our study finds the proportion to still be much higher at 32.0%.…”

“…found an increase in the overall proportion of cancers originating in the HN. Prior studies have estimated that approximately 12% of all cancer originate in the HN region, while our study finds 16.7% of pediatric tumors originated in the HN [3,14]. A more recent Danish study found the proportion to be roughly 15% [15].…”

Pediatric Oral/Maxillofacial Soft Tissue Sarcomas: A Clinicopathologic Report of Four Cases

“…The broad differential diagnosis of lesions in the OMF region is described in table 1 . The rarity of STS in this region and the preponderance of RMS noted at our institution are consistent with data from larger epidemiological studies [ 3 ]. Pathology showed overlapping poorly differentiated features, demonstrating the importance of immunohistochemistry and molecular testing in confirming the diagnoses.…”

Spectrum of head and neck cancer in children

“…Head and neck cancers were most frequent among teenagers 15–18 years old (39%), followed by children 4 years or younger (27%), 10–14 years (21%), and 5–9 years (13%). [4] The overall sex ratio in favor of the males was comparable with the studies where the male:female ratio were 1.5:1[5] and 1.16:1. [11] However, in the latter study incidence increased in girls with age and exceeded that of boys in the age group between 10 and 14 years.…”

Pediatric Head and Neck Malignancies in the United States: A 20‐Year Population‐Based Study

“…Thyroid was the most common primary site accounting for 38.4% of all tumors. This was a large increase from Albright's findings of 22.1% [3]. When only including the ages of <1-19 years, our study finds the proportion to still be much higher at 32.0%.…”

“…found an increase in the overall proportion of cancers originating in the HN. Prior studies have estimated that approximately 12% of all cancer originate in the HN region, while our study finds 16.7% of pediatric tumors originated in the HN [3,14]. A more recent Danish study found the proportion to be roughly 15% [15].…”

Pediatric Oral/Maxillofacial Soft Tissue Sarcomas: A Clinicopathologic Report of Four Cases

“…The broad differential diagnosis of lesions in the OMF region is described in table 1 . The rarity of STS in this region and the preponderance of RMS noted at our institution are consistent with data from larger epidemiological studies [ 3 ]. Pathology showed overlapping poorly differentiated features, demonstrating the importance of immunohistochemistry and molecular testing in confirming the diagnoses.…”

Spectrum of head and neck cancer in children

“…Head and neck cancers were most frequent among teenagers 15–18 years old (39%), followed by children 4 years or younger (27%), 10–14 years (21%), and 5–9 years (13%). [4] The overall sex ratio in favor of the males was comparable with the studies where the male:female ratio were 1.5:1[5] and 1.16:1. [11] However, in the latter study incidence increased in girls with age and exceeded that of boys in the age group between 10 and 14 years.…”

Pediatric Head and Neck Malignancies in the United States: A 20‐Year Population‐Based Study

“…Thyroid was the most common primary site accounting for 38.4% of all tumors. This was a large increase from Albright's findings of 22.1% [3]. When only including the ages of <1-19 years, our study finds the proportion to still be much higher at 32.0%.…”

“…found an increase in the overall proportion of cancers originating in the HN. Prior studies have estimated that approximately 12% of all cancer originate in the HN region, while our study finds 16.7% of pediatric tumors originated in the HN [3,14]. A more recent Danish study found the proportion to be roughly 15% [15].…”