Pediatric granulomatous orchitis: Case report and review of the literature

Matsumura, Misaki; Taketani, Takeshi; Horie, Akiyoshi; Mizota, Yoko; Nakata, Soichi; Kumori, Koji; Nagase, Mamiko; Harada, Yuji; Tanaka, Yuji; Yamaguchi, Seiji

doi:10.1111/ped.12749

Cited by 4 publications

(11 citation statements)

References 7 publications

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“…It was first reported by Grunberg in 1926, and is described as a non-specific inflammation of the testicles, seen in middle-aged and elderly men, with unknown etiology. 1 – 3 It is generally thought to be related to testicular trauma, urinary tract infection, or autoimmunity. 2 , 4 – 7 The clinical symptoms are atypical, usually involving one testicle; the onset may be rapid or slow, affected testicles are enlarged and hard, and these findings may be accompanied by pain and swelling.…”

Section: Discussionmentioning

confidence: 99%

Granulomatous orchitis: case report and review of the literature

Liu

Jiajia

et al. 2021

J Int Med Res

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We report the disease characteristics, diagnosis, and treatment of granulomatous orchitis. A 38-year-old man presented with a history of intermittent swelling, pain, and discomfort in the right testicle of 3 days’ duration. Unenhanced magnetic resonance imaging (MRI) of the testis and scrotum revealed an oval mass in the right testis measuring approximately 17 mm in diameter, with clear borders and a target ring-like appearance from periphery to center. T1-weighted imaging (T1WI) showed uniform low-intensity signals, and T2WI showed mixed high- and low-intensity signals. Diffusion-weighted imaging (DWI) signals were iso-intense, and the outer ring on enhanced scans showed progressive enhancement. We performed radical resection of the right testis under combined spinal–epidural anesthesia. The pathological diagnosis was granulomatous right orchitis. Two months postoperatively, ultrasonography showed no testis and epididymal echo signals in the right scrotum, and no obvious abnormalities; color Doppler blood flow imaging (CDFI) findings were normal. Granulomatous orchitis is rare in clinical practice, and the cause is unknown. The disease involves non-specific inflammation; however, it is currently believed that antibiotics and steroids are ineffective for conservative treatment, and orchiectomy should be actively performed.

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Section: Discussionmentioning

confidence: 99%

Granulomatous orchitis: case report and review of the literature

Liu

Jiajia

et al. 2021

J Int Med Res

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“…Some studies have reported that B-ultrasound-guided fine needle biopsy (FNA) has diagnostic significance for yellow granulomatous pyelonephritis and cholecystitis, and FNA is expected to become a useful tool for preoperative diagnosis of XGO [16], which may prevent orchiectomy due to unexpected diagnosis.The general management of xanthogranulomatous orchitis includes anti-inflammatory, analgesic, detumescent, and symptomatic treatment, but the effect is not ideal. Orchiectomy for [17] was ultimately chosen in many cases. In adolescents with testicular swelling and pain, anti-infective treatment is generally preferred.…”

Section: C B Amentioning

confidence: 99%

Xanthogranulomatous Orchitis Combined with Contralateral Acute Pyogenic Orchitis: A Rare Case Report

Dai,

Meng,

et al. 2024

Preprint

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Xanthogranulomatous orchitis is a chronic, non-neoplastic inflammation that is quite rare. In this paper, we discuss the case of a 79-year-old male patient who presented with bilateral scrotum swelling and dysuria that persisted for two weeks. Despite two weeks of anti-infection treatment, the patient's symptoms persisted, leading to a decision to perform transurethral prostate resection and bilateral orchiectomy after careful consideration. After the surgery, the postoperative pathology indicated that the patient had xanthogranulomatous orchitis on the left side and acute positive orchitis with hemorrhage on the right side. Fortunately, three months after the procedure, the patient experienced no negative events and was pleased with the postoperative results.

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“…Xantho-granulomatous orchitis (XGO) is a rare, nonmalignant lesion diagnosed while evaluating testicular mass. [1][2][3] Many at time, it becomes difficult to diagnose this rare entity based on clinical & radiological findings. A detailed histological evaluation is necessary to rule out any malignancy and give a definitive diagnosis of XGO.…”

Section: Introductionmentioning

confidence: 99%

“…A detailed histological evaluation is necessary to rule out any malignancy and give a definitive diagnosis of XGO. 2,3 Very few cases of XGO have been reported in the literature till date. [2][3][4][5][6][7] Here in we describe this rare entity in a 45-yearold male, who presented to hospital with right testicular swelling.…”

Section: Introductionmentioning

confidence: 99%

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Xantho-granulomatous orchitis: A rare case mimicking malignancy

Kishore,

Bhardwaj

2023

IJPO

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Testicular mass is an important and frequently encountered finding in hospital setting. Xanthogranulomatous orchitis (XGO) is an uncommon benign lesion and an important cause of testicular mass. It should always be kept as an important differential diagnosis while evaluating testicular lesions. We report a rare case of XGO in a 45-year-old male who presented with a right scrotal swelling. A provisional diagnosis of testicular mass; suspicious of malignancy was given. Right-sided orchidectomy was done. The excised mass was sent for a detailed histopathological evaluation. On histology, a definitive diagnosis of this rare entity was made.

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Pediatric granulomatous orchitis: Case report and review of the literature

Cited by 4 publications

References 7 publications

Granulomatous orchitis: case report and review of the literature

Granulomatous orchitis: case report and review of the literature

Xanthogranulomatous Orchitis Combined with Contralateral Acute Pyogenic Orchitis: A Rare Case Report

Xantho-granulomatous orchitis: A rare case mimicking malignancy

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