Pediatric Capsule Endoscopy

Cohen, Stanley A.; Ephrath, Hagit; Lewis, Jeffery D.; Klevens, Alan I.; Bergwerk, Ari; Liu, Steven; Patel, Dinesh L.; Reed-Knight, Bonney; Stallworth, Angela; Wakhisi, Tamara; Gold, Benjamin D.

doi:10.1097/mpg.0b013e31822c81fd

Cited by 46 publications

(30 citation statements)

References 20 publications

(42 reference statements)

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“…Since its introduction and approval by the US Food and Drug Administration for children ≥10 years of age in 2003, wireless CE has been increasingly used in eligible patients [37]. Supported by experience in children as young as 10 months of age, the FDA expanded the role for CE use to children two years and older and also approved the use of a patency capsule [38].…”

Section: Reviewmentioning

confidence: 99%

An update on pediatric endoscopy

Friedt

Welsch

2013

Eur J Med Res

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Advances in endoscopy and anesthesia have enabled gastrointestinal endoscopy for children since 1960. Over the past decades, the number of endoscopies has increased rapidly. As specialized teams of pediatric gastroenterologists, pediatric intensive care physicians and pediatric endoscopy nurses are available in many medical centers, safe and effective procedures have been established. Therefore, diagnostic endoscopies in children are routine clinical procedures. The most frequently performed endoscopies are esophagogastroduodenoscopy (EGD), colonoscopy and endoscopic retrograde cholangiopancreaticography (ERCP). Therapeutic interventions include variceal bleeding ligation, foreign body retrieval and percutaneous endoscopic gastrostomy. New advances in pediatric endoscopy have led to more sensitive diagnostics of common pediatric gastrointestinal disorders, such as Crohn’s disease, ulcerative colitis and celiac disease; likewise, new diseases, such as eosinophilic esophagitis, have been brought to light.Upcoming modalities, such as capsule endoscopy, double balloon enteroscopy and narrow band imaging, are being established and may contribute to diagnostics in pediatric gastroenterology in the future.

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Section: Reviewmentioning

confidence: 99%

An update on pediatric endoscopy

Friedt

Welsch

2013

Eur J Med Res

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“…The capsule endoscope (CE) is one of the most common noninvasive clinical tools in the evaluation of gastrointestinal (GI) tract disease (Cohen et al 2012). Currently millions of CEs have been used world-wide to diagnose the small-bowel and to assess GI tract performance (Liao et al 2010b).…”

Section: Introductionmentioning

confidence: 99%

A bio-inspired attachment mechanism for long-term adhesion to the small intestine

Xie

Kothari

Terry

2015

Biomed Microdevices

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To achieve long-term attachment of capsule endoscopes (CEs) and miniature biosensors in the human gastrointestinal (GI) tract, a tissue attachment mechanism (TAM) was designed, optimized and tested for safety and adhesive capabilities on excised tissue in vitro and in vivo on a live pig model. Six TAMs were tested for their attachment strength in an in vitro attachment tensile experiment in which each TAM was tested on three different proximal intestine tissue samples. The maximum strength and average value are 8.09 N and 4.54 N respectively. The initial attachment damage was tested for 10 min using a sine wave pull force on the TAM with a 0.4 N peak value and 6 s period, which represents typical human intestinal traction force from peristalsis. The in vitro attachment tensile test verified that the tissue was not visually damaged nor perforated by the attachment process. In the in vivo experiment, four TAMs were placed in the intestine of a pig through individual longitudinal enterotomies. X-ray images were taken each hour after the surgery and showed zero migration of the TAMs after 24 h of adhesion. X-ray images taken each day indicated the attachment duration of this mechanism lasted up to 6 days. Post experiment inspection confirmed the attachment did not cause visible damage to tissue. These results confirmed the reliability of the TAM in vivo and demonstrated preliminary feasibility of long-term sensor adhesion to the GI tract.

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“…If the capsule cannot be swallowed, endoscopic placement of the capsule can become necessary. A capsule retention in children is a rare side effect, reported in less than 1% of the procedures [130][131][132][133].…”

Section: Capsule Endoscopymentioning

confidence: 99%

Pediatric Endoscopy, Update 2020

et al. 2019

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Optimal management of pediatric endoscopy requires a multidisciplinary approach. In most hospitals, endoscopy in pediatric patients is performed by conventional gastroenterologists and only a few centers have specialized pediatric gastroenterologists. This is due to the fact that the number of pediatric gastroenterologists is limited and not all of them are experienced in endoscopic techniques. However, there are also some pediatric centers offering a high-quality and high-volume endoscopy service provided by very experienced pediatric gastroenterologists. Up to now, the literature on pediatric endoscopy is rather sparse. In this article, we describe current knowledge and practice of endoscopic procedures in pediatric patients, which should be relevant for both the adult and pediatric gastroenterologists.

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Pediatric Capsule Endoscopy

Abstract: CE is useful to diagnose SB disease in children. Even in a study population with a high prevalence of confirmed and suspected CD, the risk of retention remains small. The patency capsule may lessen that risk. CE may identify gastric or colonic disease even when SB lesions are not present.

Cited by 46 publications

References 20 publications

An update on pediatric endoscopy

An update on pediatric endoscopy

A bio-inspired attachment mechanism for long-term adhesion to the small intestine

Pediatric Endoscopy, Update 2020

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