Pediatric Budd-Chiari Syndrome: A Case Series

Redkar, Rajeev; Bangar, Anant; Hathiramani, Varun; Raj, Vinod; C, Swathi

doi:10.1007/s13312-018-1397-y

Cited by 9 publications

(5 citation statements)

References 8 publications

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“…[ 19 ]. Although there is literature supporting interventional radiological procedures for treating BCS in adults, minimal data is available for treating children [ 20 ]. Out of all the aforementioned interventional steps, LT is the most favorable in the pediatric age group, with lifelong anticoagulation therapy a second option.…”

Section: Discussionmentioning

confidence: 99%

Rare Case of Budd-Chiari Syndrome in a Young Child: A Diagnostic Conundrum

Timsaal¹,

Ali²,

Malik³

et al. 2021

Cureus

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Budd-Chiari syndrome (BCS) is an uncommon vascular disorder in which venous thrombosis prevents the venous outflow of the liver. The obstruction is primarily at the level of hepatic veins and inferior vena cava.Here, we present a case of a two-and-a-half-year-old male child who presented with complaints of abdominal distension for two months and fever and watery diarrhea for one month. Physical examination showed the patient was anemic with palmar erythema. He was started on an empirical treatment of cefotaxime, metronidazole, and amikacin. Sensitivity and culture reports for blood and urine samples were negative, but abdominal computed tomography (CT) scan showed characteristic findings for BCS with caudate lobe hypertrophy. After the symptomatic treatment of the patient, a liver transplant was suggested as a last resort.

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Section: Discussionmentioning

confidence: 99%

Rare Case of Budd-Chiari Syndrome in a Young Child: A Diagnostic Conundrum

Timsaal¹,

Ali²,

Malik³

et al. 2021

Cureus

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“…Pediatric BCS has also been described in the literature as a serious complication of liver transplantation, and has been reported to be successfully treated by percutaneous radiologic interventions [6] , [7] , [8] . One case series examined 25 pediatric patients with acute BCS, of which 21 patients underwent balloon angioplasty, and this was found to be a safe and successful treatment strategy, with surgical management being an appropriate attempt in failed radiological management cases [9] .…”

Section: Discussionmentioning

confidence: 99%

Acute Budd-Chiari syndrome during hepatic vein catheterization

Rohringer

Zaarour

Williams

et al. 2020

Radiology Case Reports

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This case report describes a 4-year-old male with a history of hepatoblastoma, treated with chemotherapy followed by a right extended hepatectomy. Secondary to this, the patient experienced recurrent hepatic vein stenosis. He was treated initially with conventional angioplasty, followed by paclitaxel-coated balloon dilatations in an attempt to prevent episodes of re-stenosis. During the catheterization of the hepatic vein in one of the treatments, hemodynamic instability due to an acute Budd-Chiari syndrome occurred. The hemodynamic compromise became unresponsive to intravascular resuscitation and inotropic support. The patient was then treated with an emergency conventional angioplasty of the hepatic vein, which resulted in a rapid response and eventually in a full recovery. The etiology of this complication remains unclear; however, it may have been secondary to endothelial damage leading to acute thrombosis and/or venous spasm. Conventional angioplasty was successful in managing this complication. Awareness of iatrogenic acute Budd-Chiari syndrome as a potentially fatal complication during hepatic catheterization/dilatation, especially in the posthepatectomy setting, successful management of this complication, and the importance of a multidisciplinary and rapid response, is emphasized.

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“…1 The most common causes of BCS in children are inherited hypercoagulable states such as Protein C and S deficiency. 2 In addition, decreased levels of in antithrombin III have also recently been linked to the cause of BCS which can be seen as increased values of PTT. 3 Another prominent risk factor for BCS is hyperhomocysteinemia.…”

Section: What Is the Cause Of Recurrent Thrombosis In This Child?mentioning

confidence: 99%