Pediatric bag-in-the-lens intraocular lens implantation: Long-term follow-up

Looveren, Jan Van; Dhubhghaill, Sorcha Ní; Godts, Daisy; Bakker, E.J.M.; Veuster, Ilse De; Mathysen, Danny G.P.; Tassignon, Marie-José

doi:10.1016/j.jcrs.2014.12.057

Cited by 49 publications

(75 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Van Looveren et al. () (Tassignon group) published the results after 5 years follow‐up results of bag‐in‐the‐lens in in 46 paediatric eyes operated between 2 months and 14 years of age with an overall clear visual axis in 91.3%. They reported VAR in four eyes of three patients, who were treated with anterior vitrectomy and re‐implantation of the posterior capsule into the bag‐in‐the‐lens IOL groove.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Analysis and management of intraoperative and early postoperative complications of bag‐in‐the‐lens intraocular lens implantation in different age groups of paediatric cataract patients: report of the Giessen Paediatric Cataract Study Group

Lytvynchuk

Thiele

Lorenz

2019

Acta Ophthalmologica

View full text Add to dashboard Cite

Purpose To report the rate and management of intra‐ and early postoperative complications of bag‐in‐the‐lens intraocular lens (IOL) implantation technique for cataract treatment in paediatric patients of different age groups. Settings Department of Ophthalmology, Justus‐Liebig‐University Giessen, University Hospital Giessen and Marburg GmbH, Campus Giessen, Giessen, Germany. Design Retrospective non‐randomized consecutive case series. Methods Ninety eyes of 60 paediatric cataract patients were enrolled to this retrospective non‐randomized observational consecutive case series single‐centre study. All patients underwent cataract surgery with bag‐in‐the‐lens IOL implantation between January 2008 and December 2018, performed by two experienced surgeons. The entire cohort was divided into four age groups: first – 0–<3 months, second – 3–<12 months, third – 12–<36 and fourth – >36 months–17 years of age. The intra‐ and postoperative complications were based on the clinical records. The description of management of complications related specifically to bag‐in‐the‐lens IOL technique was based on the 39 consecutive cases operated since 1 Jan 2016 by one single surgeon that were all video documented. The early postoperative period was defined as 12 months after surgery. Results Overall, there were 27 unilateral and 33 bilateral surgical cases of 24 female and 36 male children. The mean age at surgery was 45.25 months (range 1–200 months). The most common intraoperative events were vitreous prolapse and anterior capsule rupture with 28.9% and 13.3%, respectively. Within 12 months of follow‐up, five eyes (5.6%) were re‐operated because of visual axis reo‐pacification (VAR). Intraocular hypertension was diagnosed in seven eyes (7.8%), including two cases that required surgical treatment. In all cases with intra‐ and early postoperative complications related specifically to bag‐in‐the‐lens technique, it was possible to manage them and successfully implant bag‐in‐the‐lens IOL. Conclusions Implementation of bag‐in‐the‐lens technique in the treatment of paediatric cataract was associated with a relatively low rate of intra‐ and postoperative complications, including rare cases of VAR. The correct management of complications related specifically to bag‐in‐the‐lens IOL implantation technique shall to be considered during the learning curve.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The same group also reported the long‐term follow‐up results of bag‐in‐the‐lens IOL implantation in 46 eyes of 31 children (Van Looveren et al. ). Nyström et al.…”

Section: Introductionmentioning

confidence: 97%

Analysis and management of intraoperative and early postoperative complications of bag‐in‐the‐lens intraocular lens implantation in different age groups of paediatric cataract patients: report of the Giessen Paediatric Cataract Study Group

Lytvynchuk

Thiele

Lorenz

2019

Acta Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…In a long-term study of 46 eyes of 31 children, Tassignon et al showed that the technique allowed for maintenance of a clear visual axis in 91.3% of cases over 5 years 32 . Successful completion of this technique requires positioning of a specially designed IOL with a circumferential interhaptic groove in the anterior and posterior capusulotomy, allowing the leaflets of the anterior and posterior capsule to rest in the groove.…”

Section: Five-year Viewmentioning

confidence: 99%

Evaluating the evidence for and against the use of IOLs in infants and young children

Kumar

Lambert

2016

Expert Review of Medical Devices

View full text Add to dashboard Cite

Summary Congenital cataracts account for 5–20% of childhood blindness worldwide. In the US, the prevalence of visually significant infantile cataracts is anywhere from 3–4 per 10,000 live births. Infantile cataracts need to be removed early in life in order to prevent the onset of deprivation amblyopia. As a result, cataract surgery is usually performed between age 4–8 weeks depending on the laterality and severity of the cataract. Given advances in the field, pediatric cataract surgery is now a safe and effective intervention for infants, but good visual outcomes require occlusion therapy and optical correction. This review will address current perspectives on the use of intraocular lenses to optically correct infants and young children after cataract surgery, as well as novel designs for intraocular lenses and directions for future research.

show abstract

“…A PCP, strongly adherent to the internal surface of the posterior lens capsule, is however often found in these idiopathic unilateral paediatric cataract cases (Wilson et al 2011). Although performing anterior vitrectomy is often advocated during cataract surgery in pre-schooled children to prevent postoperative visual axis reopacification, it is not mandatory when using the bag-in-the-lens IOL implantation technique as it was the case in all four children (Van Looveren et al 2015). All PCP samples included in this study were collected from children presenting with unilateral paediatric cataract, but with a large variation in degree of lens opacification as described in literature (from a completely clear lens to a completely white cataract) (Wilson et al 2011).…”

Section: Discussionmentioning

confidence: 97%

Proteomic analysis of posterior capsular plaques in congenital unilateral cataract

Looveren

Gerwen

Schildermans

et al. 2018

Acta Ophthalmologica

Self Cite

View full text Add to dashboard Cite

Purpose: To obtain insights on the protein composition of posterior capsular plaques (PCP) in congenital unilateral cataract with anterior vitreolenticular interface dysgenesis (AVLID). Methods: Posterior capsular plaque's were collected during surgery in children presenting with congenital unilateral cataract. Surgeries were analysed focusing on the type of cataract, the integrity of the posterior capsule after peeling the PCP and the presence of vitreolenticular adherences when performing primary posterior capsulorhexis. Proteome analysis was performed on the collected PCPs. Results: Posterior capsular plaques collection and proteome analysis were feasible from four children presenting with unilateral idiopathic congenital cataract and AVLID. A large portion of the proteins found in the PCPs was similar to the proteins known to be present in lens epithelial cells and fibres. Proteins like vimentin, fibronectin, collagen type I, collagen type VI and lumican were also found, which typically are present in mesenchymal tissue but not in lens tissue or capsule. Conclusion: Posterior capsular plaques in cases of unilateral idiopathic congenital cataract of the AVLID type present a protein composition of mainly proteins found in lens epithelial cells and fibres. Some proteins however are a specific for lens tissue and are typically seen in mesenchymal tissue.

show abstract

Pediatric bag-in-the-lens intraocular lens implantation: Long-term follow-up

Cited by 49 publications

References 27 publications

Analysis and management of intraoperative and early postoperative complications of bag‐in‐the‐lens intraocular lens implantation in different age groups of paediatric cataract patients: report of the Giessen Paediatric Cataract Study Group

Analysis and management of intraoperative and early postoperative complications of bag‐in‐the‐lens intraocular lens implantation in different age groups of paediatric cataract patients: report of the Giessen Paediatric Cataract Study Group

Evaluating the evidence for and against the use of IOLs in infants and young children

Proteomic analysis of posterior capsular plaques in congenital unilateral cataract

Contact Info

Product

Resources

About