Pediatric Acute Respiratory Distress Syndrome

Abstract

This pediatric-specific definition for acute respiratory distress syndrome builds on the adult-based Berlin Definition, but has been modified to account for differences between adults and children with acute respiratory distress syndrome. We propose using this definition for future investigations and clinical care of children with pediatric acute respiratory distress syndrome and encourage external validation with the hope for continued iterative refinement of the definition.

The Berlin definition met our needs: yes

“…Since its publication in 2012 it has been cited more the 1500 times and is the subject of more than 150 articles on PubMed. Furthermore, the Pediatric Acute Lung Injury Consensus Conference used the Berlin criteria for the development of the pediatric ARDS definition [13,14]. Finally, the Berlin definition is used in a remarkable number of ongoing clinical trials in ARDS (Table 1).…”

High frequency oscillatory ventilation versus conventional mechanical ventilation in pediatric acute respiratory distress syndrome: A randomized controlled study

“…Khemani et al 5 reviewed seven PARDS studies 10,11,15,18,53,56,57 and found stepwise increases in mortality as the OI severity increases between OI groups (4-8 group, 8-16 group and >16 group).…”

“…In 2012 the Berlin definition was developed as it showed a better predictive validity for mortality 4 . However, in 2015 the Pediatric Acute Lung Injury Consensus Conference (PALICC) proposed a pediatricspecific definition for acute respiratory distress syndrome which builds on the adult-based Berlin Definition, but has been modified to account for differences between adults and children with acute respiratory distress syndrome, suggesting using this definition for future investigations and clinical care of children with pediatric acute respiratory distress syndrome 5 .…”

“…High frequency oscillation appeared as an alternative technique of ventilation in which extremely small tidal volumes (1-3 ml/kg) are delivered at high frequencies (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) with an oscillatory pump and constant lung recruitment 26 , hence it meets theoretically the goals of a strategy of lung protective ventilation 27 .…”

Особливості Діагностики Гострої Дихальної Недостатності У Дітей Із Сепсисом

“…Вста-новлено, що у дітей, як і у дорослих пацієнтів, дане захворювання може розпочатися впродовж 1 тижня після дії етіологічного фактора, наявність супутньої гострої лівошлуночкової серцевої недостатності по-тенціює прояви ГРДС; також необхідною є іденти-фікація тих пацієнтів, які становлять групу ризику щодо розвитку ГРДС [7].…”