Pediatric acute renal failure in southwestern Nigeria

Olowu, Wasiu A.; Adelusola, Kayode A

doi:10.1111/j.1523-1755.2004.00918.x

Cited by 89 publications

(124 citation statements)

References 13 publications

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“…By contrast, options for RRT in pediatric AKI in many parts of sub-Saharan Africa are limited (1)(2)(3)(4). Although continuous RRT is commonly used in the management of pediatric AKI in resourcerich countries, and although it may have some advantages in the hemodynamically unstable patient, it is rarely used in the management of AKI in many parts of sub-Saharan Africa because it is expensive and requires both sophisticated technology and consumables that are generally unavailable (5).…”

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confidence: 99%

Peritoneal Dialysis in Childhood Acute Kidney Injury: Experience in Southwest Nigeria

Ademola¹,

Asinobi²,

Ogunkunle³

et al. 2012

Perit Dial Int

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BackgroundThe choices for renal replacement therapy (RRT) in childhood acute kidney injury (AKI) are limited in low-resource settings. Peritoneal dialysis (PD) appears to be the most practical modality for RRT in young children with AKI in such settings. Data from sub-Saharan Africa on the use of PD in childhood AKI are few.MethodsWe performed a retrospective study of children who underwent PD for AKI at a tertiary-care hospital in southwest Nigeria from February 2004 to March 2011 (85 months).ResultsThe study included 27 children (55.6% female). Mean age was 3.1 ± 2.6 years, with the youngest being 7 days, and the oldest, 9 years. The causes of AKI were intravascular hemolysis ( n = 11), septicemia ( n = 8), acute glomerulonephritis ( n = 3), gastroenteritis ( n = 3), and hemolytic uremic syndrome ( n = 2). Peritoneal dialysis was performed manually using percutaneous or adapted catheters. Duration of PD ranged from 6 hours to 12 days (mean: 5.0 ± 3.3 days). The main complications were peritonitis ( n = 10), pericatheter leakage ( n = 9), and catheter outflow obstruction ( n = 5). Of the 27 patients, 19 (70%) survived till discharge.ConclusionsIn low-resource settings, PD can be successfully performed for the management of childhood AKI. In our hospital, the use of adapted catheters may have contributed to the high complication rates. Peritoneal dialysis should be promoted for the management of childhood AKI in low-resource settings, and access to percutaneous or Tenckhoff catheters, dialysis fluid, and automated PD should be increased.

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mentioning

confidence: 99%

Peritoneal Dialysis in Childhood Acute Kidney Injury: Experience in Southwest Nigeria

Ademola¹,

Asinobi²,

Ogunkunle³

et al. 2012

Perit Dial Int

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“…The proportion of cases of acute renal failure that correspond to acute postinfectious glomerulonephritis of demonstrated or assumed poststreptococcal etiology is 13% in New Delhi, 44 30% in Istanbul, 45 51.6% in Casablanca, 46 4.6% in Lagos, 47 27% in Bombay, 48 19.2% in Lucknow, 49 33% in Asunció n, 50 17.4% in Chandrigarth, 51 5.2% in Lima, 52 9.3% in Varanasi, 53 and 25% in Osun State, Nigeria. 54 …”

mentioning

confidence: 99%

The Current State of Poststreptococcal Glomerulonephritis

Rodríguez‐Iturbe¹,

Musser²

2008

Journal of the American Society of Nephrology

243

172

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“…Olowo et al 22 found higher incidence of HUS and glomerulonephritis. Many of the cases with ARF were secondary to Burkitt's lymphoma.…”

Section: Comparison With Nephrotic Syndrome In Elderlymentioning

confidence: 99%

Study of paediatric renal biopsies with clinicopathologic correlation and comparison with literature on adult renal biopsies

2020

IJPO

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Introduction: Renal biopsy is frequently used in complete work-up for renal diseases. The kidney reacts in a limited number of patterns to various injuries and the clinical manifestations corresponding to these reactions are also limited. Aim of the study: To study the non-neoplastic renal diseases in paediatric population 0-15 year age, to study the differences in the disease prevalence between paediatric and adult population, and to document the geographic variation in renal diseases. Materials and Methods:The renal biopsies from 0-15 year age group of both genders were studied for light microscopy and immunofluorescence studies. The clinical presentation of the patients such as nephrotic or nephritic or both or as acute renal failure was noted for clinic pathologic correlation. The paediatric renal diseases were compared with adult renal diseases based on literature search. Also the geographic variations were studied and compared based on published data from different countries. Results: Nephrotic syndrome was the most common clinical presentation for paediatric renal diseases .Minimal change disease (37.8 %) and FSGS (22.4 %) cases commonly presented as nephrotic syndrome. PIGN (37.6 % cases) presented frequently as nephritic syndrome in the paediatric age group. Conclusion: Nephrotic syndrome is the most common indication for renal biopsy and minimal change disease is the commonest cause of nephrotic syndrome in children. Incidence of membranous nephropathy and IgA nephropathy is relatively less in India. PIGN is the most common cause of acute renal failure in the paediatric age group. In systemic lupus erythematosus, most common presentation is nephrotic syndrome with class IV lupus nephritis being more frequent.

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Pediatric acute renal failure in southwestern Nigeria

Abstract: These results show that many of the causes of ARF in our patients are preventable; it should be possible to reduce morbidity due to ARF through purposive preventive measures.

Cited by 89 publications

References 13 publications

Peritoneal Dialysis in Childhood Acute Kidney Injury: Experience in Southwest Nigeria

Peritoneal Dialysis in Childhood Acute Kidney Injury: Experience in Southwest Nigeria

The Current State of Poststreptococcal Glomerulonephritis

Study of paediatric renal biopsies with clinicopathologic correlation and comparison with literature on adult renal biopsies

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