Pectoserratus plane block versus erector spinae plane block for postoperative opioid consumption and acute and chronic pain after breast cancer surgery: A randomized controlled trial

Genç, Caner; Kaya, Cengiz; Bilgin, Sezgin; Dost, Burhan; Üstün, Yasemin Burcu; Köksal, Ersin

doi:10.1016/j.jclinane.2022.110691

Cited by 10 publications

(12 citation statements)

References 28 publications

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“…Two studies 36,37 reported long‐term postoperative chronic pain. The study by Genc et al 36 showed that the control group was significantly higher than the experimental group in terms of chronic pain scores assessed at 3 months postoperatively (ESPB = 0; control = 1; p < 0.001). In addition, the control group had a higher incidence of chronic pain than the ESPB group (ESPB = 23%; Control group = 70%, p < 0.001).…”

Section: Resultsmentioning

confidence: 99%

“…The number of patients in each group ranged from 25 to 67. Concerning surgical approach, 1 study 37 received elective unilateral immediate breast reconstruction, 12 studies 18,19,[23][24][25][27][28][29][31][32][33][34] received modified radical mastectomy, 4 included sentinel lymph node biopsy, 18,33,35,36 and 4 included axillary lymph node dissection. 25,26,33,35 Of these, 2 studies 18,27 performed ultrasound-guided ESPB nerve blocks in the period following general anesthesia and before surgery began, and 1 study 20 performed after surgery, with the remaining 17 studies conducted before general anesthesia, with or without preoperative sedation.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Two studies 36,37 reported long-term postoperative chronic pain. The study by Genc et al 36 showed that the control group was significantly higher than the experimental group in terms of chronic pain scores assessed at 3 months postoperatively (ESPB = 0; control = 1; p < 0.001).…”

Section: Postoperative Chronic Painmentioning

confidence: 99%

“…The basic characteristics of the participating studies are shown in Table 1. Of all breast cancer surgery patients in the 20 included trials, [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] there were 649 patients in the ESPB group and 644 patients in the GA group. The number of patients in each group ranged from 25 to 67.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Sensory blocks were assessed in 7 of 20 trials, all of which were successful. 18,22,26,29,30,32,34,36…”

Section: Study Characteristicsmentioning

confidence: 99%

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Efficacy and safety of erector spinae plane block for postoperative analgesia in breast cancer surgery—A systematic review and meta‐analysis

Guan

Yuan

Gao

et al. 2023

Journal of Surgical Oncology

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Background and Objectives We aim to evaluate the analgesic efficacy and safety of erector spinae plane block (ESPB) for postoperative analgesia in breast cancer surgeries. Methods PubMed, Web of Science, CBM, Embase, Cochrane, Wanfang, VIPP, and CNKI were searched to identify published eligible randomized controlled trials. The primary results were the postoperative 24 h morphine consumption and pain scores, while the secondary outcomes included pain scores at other times, press times of patient‐controlled intravenous analgesia (PCIA), times to request for first rescue analgesia, the incidence of request for rescue analgesia, opioid‐related complications, nerve blocks related complications and patient satisfaction. Results We included 20 studies meeting the inclusion criteria, which involved 1293 participants. The morphine consumption and the pain scores during 24 h postoperatively were significantly decreased in the ESPB group versus the control group (p < 0.00001). Furthermore, ESPB also reduced pain scores at other time points, press times of PCIA, and times to first rescue analgesia requirement. Meanwhile, there was a lower incidence of postoperative nausea and vomiting, and skin pruritus in the ESPB group than in the control group. Conclusions Compared to general anesthesia alone, ESPB combined with general anesthesia can effectively reduce the postoperative pain intensity within 48 h and opioid consumption within 24 h after breast cancer surgery, and reduce the incidence of opioid and nerve blocks related complications.

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Section: Resultsmentioning

confidence: 99%