Peak troponin I level predicts new-onset atrial fibrillation in patients with myocardial infarction

Abstract

Purpose: We aimed to assess the predictive value of peak troponin I level for the occurrence of new-onset AF in myocardial infarction. Methods: A total of 1553 patients, who were hospitalized with diagnosis of STEMI and underwent primary PCI, were retrospectively evaluated. New-onset AF was defined as any newly diagnosed AF that occurred during index hospitalization after primary PCI. Results: New-onset AF was observed in 90 patients (5.8% of the study population). Patients who developed AF were older (56.1 vs. 62.6 years, p

New-Onset Atrial Fibrillation in the Post-Primary PCI Setting: A Systematic Review

“…Zehir [21] NA NA Karataş [22] NA 27 vs. 5%, P < 0.001. HR: 2.20 (95% CI 1.03-4.72), P = 0.040 Olsen [23] NA NA Garg [24] 10.3% vs 9.4%.…”

“…The studies found a predictive relationship between laboratory parameters and subsequent incidence of NOAF. A strong association was found with elevated cardiac biomarkers including troponin and BNP [17,21,26,31,32]. Various hematological indices were regarded as predictors of the NOAF development [21,22,32].…”

“…Several studies aimed at identifying clinical variables that independently predict NOAF in STEMI patients. Analysis of data showed that independent predictors of NOAF following primary PCI were advancing age [13,16,18,19,21,22,27,29,30,32] and signs indicating extensive myocardial damage indicated by tachycardia [13,22], hypotension [18], cardiogenic shock [30], higher Killip class [13,16,18,21] and poor LV function (represented by LV EF) [21,22,29].…”

“…Angiographic characteristics of the infarct-related artery including total occlusion, fi nal low TIMI fl ow [18], the RCA as the culprit artery [16], complexity of coronary artery lesions represented by Syntax score, and the Syntax score II [29] as well as failed PCI procedures [21] were frequently found in patients with NOAF.…”

“…Other reported predictors are a previous history of MI [27] and revascularization [21], male gender [13], impairment of renal function [18], body mass index [19,32], LA size [22,30] and function [33] by echocardiography, and a higher CHA2DS2VASc score [31].…”