Abstract:Objectives: We estimated the cost-effectiveness of once-weekly semaglutide 1 mg vs. canagliflozin 300 mg in Canada from the payer and societal perspectives. Methods: Modeling methods were used to extrapolate benefits observed in the SUSTAIN 8 clinical trial into long-term costs and outcomes, measured by qualityadjusted life-years (QALYs), for patients treated with semaglutide or canagliflozin. The SUSTAIN 8 trial, a 52-week, randomized, double-blind clinical trial, demonstrated significantly greater lowering o… Show more
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